Creatine Supplementation and Bone Mass

Not Applicable

Completed

• Conditions: Osteopenia; Osteoporosis
• Interventions: Dietary Supplement: creatine supplementation; Other: placebo (dextrose); Other: exercise training

• Registration Number: NCT01163370
• Lead Sponsor: University of Sao Paulo

Brief Summary

Resistance training as well as creatine supplementation may increase bone mass. Therefore, the investigators speculate that resistance training combined with creatine supplementation would promote additive benefits on bone mass in elderly women with osteopenia and osteoporosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07
• Study First Submitted: 2010-07-14
• Study First Submitted QC: 2010-07-14
• Study First Posted: 2010-07-15
• Primary Completion: 2011-08
• Study Completion: 2011-08
• Status Verified: 2011-11
• Last Update Submitted: 2011-11-09
• Last Update Posted: 2011-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• osteopenia and osteoporosis
• women older than 60 years old

Exclusion Criteria

• cardiovascular diseases or muscular disturbances precluding exercise training
• drugs affecting bone metabolism

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
control and exercise	placebo (dextrose)	this is trained and receives placebo
creatine	creatine supplementation	this is non-exercise trained and receives creatine supplementation
exercise and creatine	creatine supplementation	this is exercised trained and receives creatine supplementation
exercise and creatine	exercise training	this is exercised trained and receives creatine supplementation
placebo	placebo (dextrose)	this only receives placebo (dextrose)
control and exercise	exercise training	this is trained and receives placebo

Primary Outcome Measures

Name	Time	Method
bone mineral density	six months

Secondary Outcome Measures

Name	Time	Method
cognition	six months
physical capacity	six months	including muscle strength, balance and muscle function

Trial Locations

Locations (1)

School of Medicine - Division of Rheumatology; 🇧🇷 Sao Paulo, Brazil