Determine the effect of Simvastatin to control negative symptoms of atypical antipsychotics in patients with schizophrenia

Vice Chancellor for Research, Ahwaz University of Medical Sciences0 个研究点目标入组 40 人开始时间: 待定最近更新: 2018年2月22日

适应症

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•Inclusion criteria for this study: having a diagnosis of schizophrenia according to DSM-IV-TR? a PANSS total score of 50 or higher on the scale? the scale PANSS negative score of 15 or more of 70-18 years, during a period of at least 1 year of disease onset.
•Exclusion criteria for this study: patients with a history of sensitivity to statins ? active liver disease or increase stability and unexplained liver enzymes? kidney failure? medical condition serious? drug abuse or drug dependence during the previous month? pregnancy? lactation? there at the same time other psychiatric disorders requiring drug therapy? desire to commit suicide or homicide? possession of dementia and cognitive impairment serious? unrelated to schizophrenia? organic disease of the brain such as seizures and severe mental retardation and Parkinson's disease, Taking anti psychotic oral over the past month or long-acting injections over the past three months? the concomitant use of other drugs such as antidepressants or lithium? etc. which may be a result of treatment interfere? schizophrenia resistant to treatment? lack of response to an adequate dose and appropriate for typical anti psychotic drugs.

发起方

Vice Chancellor for Research, Ahwaz University of Medical Sciences