MedPath

Technology and Family Thriving Study

Not Applicable
Completed
Conditions
Dementia
Alzheimer Disease
Quality of Life
Caregiver Burnout
Mental Health Wellness 1
Loneliness
Family Relationship
Interventions
Behavioral: Virtual Reality
Behavioral: Video Chat
Registration Number
NCT05150990
Lead Sponsor
University of California, Santa Barbara
Brief Summary

The purpose of this project is to test the impact of different forms of technology (virtual reality vs. video chat) on quality of life and family relationships in older adults who reside in senior living communities and an adult child who lives at a distance. The study will also investigate whether responses to the technology and quality of life outcomes depend on older adults' level of cognitive impairment.

Detailed Description

Purpose of the clinical trial: The virtual reality (VR) program, Rendever, enables older adults in senior living communities to maintain important family relationships, engage fully with life, and reconnect with their past, regardless of physical location, through its advanced networking and live-streaming capabilities. This project will test the immediate and longer-term impact of the Rendever virtual reality platform (vs. video chat) on the quality of life of residents and their adult children in an experimental design. The study will also investigate whether responses to the technology and quality of life outcomes depend on older adults' level of cognitive impairment.

Participants: Participants will be older adults (age 50+) with mild cognitive impairments (MCI) or mild to moderate Alzheimer's Disease or related dementias (AD/ADRD) who reside in senior living communities, and an adult child who lives at a distance. The resident-adult child dyads (N=192 dyads) will be recruited from 12 senior living communities in the greater Boston area and central California. Residents will participate from their senior living community and adult children will participate from their own home, at least 45 minutes driving distance away.

Study Design and Method: The design is a 2 (Intervention Group: Virtual Reality vs. Active Control) x 2 (Level of Cognitive Impairment: MCI vs. AD/ADRD) x Time (7 time points) design. Dyads will be randomly assigned to an intervention group (Virtual Reality vs. Video Chat Control). Dependent variables will include positive engagement while using the technology, quality of life, psychological and social well-being (loneliness, mental health, thriving, and relationship quality), and caregiver guilt (guilt, stress, and burden) assessed through surveys, interviews, and observational methods.

The experimental intervention will be implemented in a between-group design. Dyads will be randomly assigned to either the Virtual Reality Condition or the active Control Condition (video chat). Participants will complete a baseline survey (T1), followed by four activity sessions once a week for 4 consecutive weeks (T2-T5). Follow-up surveys will be conducted at 1-month (T6) and 3-months (T7) post-intervention. Residents and adult children will also be interviewed briefly after the intervention and at the each follow-up. All sessions will be video and audiotaped. Computerized and human coding will examine positive engagement and interpersonal dynamics while using the technology.

Dyads assigned to the virtual reality (VR) condition will engage in 4 weekly VR sessions that include immersive virtual adventures (e.g., bucket list travel) and reminiscence activities (e.g., virtual life story). Dyads assigned to the control condition will engage in 4 weekly video chat sessions. During these sessions, dyads will engage in conversations that are typical in their daily lives. All other procedures will be identical in the two conditions.

Sample size, recruitment, and statistical power: A power analysis using simulation methods (for multi-level regression models and structural equation models) was used to determine the sample size. A sample size of 192 dyads (96 in each intervention condition) evenly split between cognitive impairment groups (MCI vs. dementia) will achieve a high level of power for detecting the minimal expected effect size. Additional dyads will be recruited to account for attrition.

Statistical analysis: Because data from parent-adult child dyads will be dependent, and because the dyad is the unit of analysis for assignment to experimental conditions, the analysis of quantitative data will utilize linear models designed for nested (clustered) data. Hypothesis testing will be conducted with multi-level, random-effects regression and multi-level structural equation modeling.

Study Aims:

AIM 1: Determine whether virtual reality (vs. control) improves quality of life for residents and their adult children who live at a distance.

AIM 2: Determine whether the positive effects of virtual reality (vs. control) on quality of life depend upon residents' level of cognitive impairment (MCI vs. mild to moderate AD/ADRD).

AIM 3: Determine whether virtual reality (vs. control) reduces caregiver guilt for adult children and whether these effects depend on the adult child's own responses to the technology and their parent's responses to the technology.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
372
Inclusion Criteria

Not provided

Read More
Exclusion Criteria
  • severe AD/ADRD
  • history of severe vertigo, hallucinations, or aggression
  • severe visual impairment (screening will be conducted to determine if vision is sufficient to participate)
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Virtual RealityVirtual RealityWeekly activities using virtual reality (Rendever)
Video ChatVideo ChatWeekly activities using video conference (Zoom)
Primary Outcome Measures
NameTimeMethod
Center for Epidemiological Studies Depression Scale Revised Short Form (CESD-R-10) - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

CESD-R-10 (Björgvinsson, Kertz, Bigda-Peyton, McCoy, Aderka,2013) is a 10-item measure of depressive symptoms adapted from the longer CESD (completed by the adult child). Items are rated on a 4-point scale: 0=Rarely or none of the time, 1=Some or a little of the time, 2=Occasionally or a moderate amount of the time, 3=All of the time. Total score is the sum of the 10 items, some reverse-scored (range: 0 to 30).

Quality of Life in Alzheimer's Disease (QOL-AD) - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

QOL-AD (R.G. Logsdon, 1996) is a 13-item self-report measure of quality of life (completed by older adult and adult child informant, who reports on parent's quality of life). Items are rated on a 4-point scale: Poor = 1, Fair = 2, Good = 3, Excellent = 4. Total score is the sum of all items (range: 13 to 54). Higher scores indicate greater quality of life.

Revised UCLA Loneliness Scale (short form) - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

The short form of the Revised UCLA Loneliness Scale (Hughes, Waite, Hawkley, \& Cacioppo, 2008) is a 4-item scale widely used in field research with older adults, and adapted from the original scale (Russell D, Peplau LA, Cutrona CE, 1980). (Completed by the older adult and the adult child.) Items are rated on a 4-point scale: 1=Never, 2=Rarely, 3=Sometimes, 4=Often. Total score is the sum of the 4 items (range: 4 to 16). Higher scores indicate greater loneliness.

Brief Inventory of Thriving (BIT) - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

BIT (Su, R., Tay, L., \& Diener, E., 2014) is a 10-item self-report measure of thriving (completed by the older adult and adult child). Items are rated on a 5-point scale: 1= Strongly Disagree, 2=Disagree, 3 = Neither Agree nor Disagree, 4 = Agree, 5=Strongly Agree. Total score is the average of the 10 items (range: 1 to 5). Higher scores indicate greater sense of thriving.

Geriatric Depression Scale (GDS) - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

GDS (Sheikh, J.I., \& Yesavage, J.A., 1986) is a 15-item self-report measure of depression (completed by older adult). Items are rated "Yes" or "No" and are scored "1" if the response reflects depressive symptoms. Total score is the sum of all items (range: 0 to 15). Higher scores indicate greater depression.

Positive and Negative Affect Schedule (PANAS) - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

This scale includes 17-items from the longer PANAS (Watson, Clark, \& Tellegen (1988). (Completed by the older adult and adult child.) Participants rate the degree to which they experienced positive and negative emotions during the past week. Items are rated on a 5-point scale: 1=Not at all, 2=A little, 3=Moderately, 4=Quite a lot, 5=Extremely. Separate scores are computed for positive and negative emotion. Higher scores indicate greater positive/negative affect.

Perceived Stress Scale (PSS) - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

The PSS short form (completed by older adult and adult child) is a 4-item scale adapted from the longer PSS (Cohen, Kamarck, \& Mermelstein, 1983). Items are rated on a 5-point scale: 1=Never, 2=Almost never, 3=Sometimes, 4=Fairly often, 5=Very often. Total score is the average of the 4 items, some reverse-scored (range: 1 to 5). Higher scores indicate greater perceived stress.

Caregiver Guilt and Grief Scale - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

This scale (completed by the adult child) includes 13-items adapted from the caregiver guilt and grief scales (Wells, Jorm, Jordan, \& Lefroy, 1990). Items are rated on a 5-point scale: 1= Not at all, 2=A little, 3=A moderate amount, 4=A lot, 5=Almost unbearably. Total score is the average of the 13 items (range: 1 to 5). Higher scores indicate greater caregiver guilt/grief.

Unidimensional Relationship Closeness Scale - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

Relationship closeness is assessed with 4-items from the Unidimensional Relationship Closeness Scale (Dibble, Levine, \& Park, 2011). (Completed by the older adult and adult child). Items are rated on a 7-point scale: 1=Strongly disagree, 2=Disagree, 3=Somewhat disagree, 4=Neutral, 5=Somewhat agree, 6=Agree, 7=Strong Agree. Total score is the average of the 4 items (range: 1 to 7). Higher scores indicated greater relationship closeness.

Communal Coping - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

Communal coping is assessed with 3 items assessing feelings of unity when combatting stress (Afifi et al., 2019). Items are rated on a 5-point scale: 1=Strongly disagree 2=Disagree, 3=Neutral, 4=Agree, 5=Strongly agree. Total score is the average of the 3 items. Higher scores indicate greater sense of communal coping.

Relational Burnout/Load Scale - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

Relational burnout/load is assessed with 5 items from the Relational Load Scale (Afifi et al., 2019). (Completed by the adult child.) Items are rated on a 5-point scale: 1=Strongly disagree 2=Disagree, 3=Neutral, 4=Agree, 5=Strongly agree. Total score is the average of the 6 items, some reverse-scored (range: 1 to 5). Higher scores indicate greater sense of relational load/burnout.

Mental Health Inventory (MHI) - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

The MHI includes 8 items from the longer MHI (McHorney, Ware, \& Raczek, 1993) to assess depression, anxiety, and vitality during the past week (completed by the older adult and adult child). Items are rated on a 5-point scale: 1= None of the time, 2= A little of the time, 3=some of the time, 4=most of the time, 5= All of the time. Total score is the average of all 8 items, some reverse-scored (range: 1 to 5). Higher scores indicate better mental health.

Relationship satisfaction - changes from BaselineBaseline (1-week Pre-intervention), 1-week Post-intervention, 1-month Post-intervention, 3-months post-intervention

Global relationship satisfaction is assessed with 3 items adapted from Huston et al.'s (1986) relationship satisfaction scale (completed by the older adult and adult child). Items are rated on a 6-point scale: 1=not at all, 2=A little, 3=Somewhat, 4=Very, 5= Almost completely, 6=Completely. Total scores are the average of the 3 items (rage: 1 to 6). Higher scores indicate greater relationship satisfaction.

Secondary Outcome Measures
NameTimeMethod
Positive and Negative Affect Schedule (PANAS)Immediately after each of the 4 technology sessions during the intervention (one week apart)

Positive and negative emotions experienced during the technology session (older adult and adult child). Rated on a scale from 1 to 5, and separate indexes are computed for positive emotion and negative emotion. Higher scores represent greater positive and negative emotion. Scores will be averaged across the intervention period (4 weeks) for overall measures of positive/negative affect experienced during the intervention.

Relationship satisfaction and Communication QualityImmediately after each of the 4 technology sessions during the intervention (one week apart)

Multiple items designed to assess features of relationship quality (older adult and adult child). Higher scores represent greater satisfaction and communication quality. Scores will be averaged across the intervention period (4 weeks) for an overall score of relationship satisfaction and communication quality during the technology sessions, during the intervention period.

Social and Conversational EngagementImmediately after each of the 4 technology sessions during the intervention (one week apart)

Rating of social engagement during the technology session (older adult and adult child). Items written for this study based on the funded pilot study. Higher scores represent greater engagement. Scores will be averaged across the intervention period (4 weeks) for an overall score of engagement during the intervention.

Telepresence and CopresenceImmediately after each of the 4 technology sessions during the intervention (one week apart)

Rating of engagement and immersion during the technology session (older adult and adult child). Items written for this study based on the funded pilot study. Higher scores represent greater telepresence and co-presence. Scores will be averaged across the intervention period (4 weeks) for an overall score of telepresence and copresence experienced during the technology sessions.

Trial Locations

Locations (27)

Gardens on Hope

🇺🇸

Santa Barbara, California, United States

Maravilla

🇺🇸

Santa Barbara, California, United States

Atterdag Village of Solvang

🇺🇸

Solvang, California, United States

Stone Hill at Andover

🇺🇸

Andover, Massachusetts, United States

Youville House Assisted Living

🇺🇸

Cambridge, Massachusetts, United States

Laurelwood at The Pinehills

🇺🇸

Plymouth, Massachusetts, United States

Bayberry at Emerald Court

🇺🇸

Tewksbury, Massachusetts, United States

Autumn Glen at Dartmouth

🇺🇸

South Dartmouth, Massachusetts, United States

Brightview North Andover

🇺🇸

North Andover, Massachusetts, United States

Benchmark of Norwood (Clapboardtree)

🇺🇸

Norwood, Massachusetts, United States

Ledgewood Bay Assisted Living

🇺🇸

Milford, New Hampshire, United States

Carriage House at Lee's Farm

🇺🇸

Wayland, Massachusetts, United States

Grace Village Apartments

🇺🇸

Santa Barbara, California, United States

Belmont Calabasas

🇺🇸

Calabasas, California, United States

Ojai Gables

🇺🇸

Ojai, California, United States

Garden Court on De La Vina

🇺🇸

Santa Barbara, California, United States

Oakmont of Camarillo

🇺🇸

Camarillo, California, United States

Friendship Manor

🇺🇸

Goleta, California, United States

Casa Dorinda

🇺🇸

Montecito, California, United States

Covenant Living at the Samarkand

🇺🇸

Santa Barbara, California, United States

Vista Del Monte

🇺🇸

Santa Barbara, California, United States

Heritage House

🇺🇸

Santa Barbara, California, United States

Cadbury Commons

🇺🇸

Cambridge, Massachusetts, United States

Brightview Canton

🇺🇸

Canton, Massachusetts, United States

The Linden at Danvers

🇺🇸

Danvers, Massachusetts, United States

Valle Verde

🇺🇸

Santa Barbara, California, United States

Stonebridge at Burlington

🇺🇸

Burlington, Massachusetts, United States

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