Investigating the Effects of Sleep Restriction Therapy for Insomnia on Circadian Timing

niversity of Oxford0 个研究点目标入组 18 人开始时间: 2019年3月15日最近更新: 2021年2月16日

适应症

试验速览

2020 results in https://doi.org/10.1111/jsr.13260 (added 01/02/2021)

•1. Participant is willing and able to give informed consent for participation in the study.
•2. Male or Female, aged 25-55 years
•3. Screen positive for persistent insomnia (chronicity >3 months) as indicated on the Sleep Condition Indicator and meet DSM-5 criteria for insomnia disorder
•4. Sleep efficiency < 85%
•5. Intermediate chronotype as indicated by the Morningness-Eveningness questionnaire (score between 31 and 69)
•6. Participant is able to comply with study procedures
•7. Body mass index between 18 and 30 kg/m2

•1. Clinically significant anxiety or depressive symptoms (Anxiety (HADS) > 10)
•2. Psychiatric diagnoses other than insomnia
•3. Previous or current engagement with psychological treatment for insomnia (by healthcare professional or online)
•4. Additional sleep disorder diagnosis or positive screen (e.g. Narcolepsy, circadian rhythm disorder)
•5. Sleep-disruptive medical comorbidity or conditions contraindicated for SRT (e.g. epilepsy)
•6. Current prescription of CNS or hormonal medication
•7. Overnight, early morning, evening, or rotating shift work in the last 3 months
•8. Pregnancy, lactation, perimenopausal or menopausal
•9. Travelled across more than 2 time zones in the prior 3 months
•10. Smoked more than 5 cigarettes/week in the previous 3 months
•11. Consumed more than 300mg of caffeine per day on average
•12. Extreme alcohol consumption (score >10 on the alcohol use disorders identification test = AUDIT)
•13. Any comorbidities that are causing the sleep problems
•14. History of drug abuse in the past 12 months

发起方