Effects of Coffee Roasting on Blood Sugar Levels in Healthy Humans
- Conditions
- Hyperglycemia
- Registration Number
- NCT05119153
- Lead Sponsor
- North Carolina State University
- Brief Summary
The present study determined the effects light, medium, and dark roasted, brewed coffees on blood glucose responses in normal (n = 19) subjects.
- Detailed Description
This is a single-blinded, randomized partial block design conducted over 6 weeks in two parts.
In part 1 (3 weeks), participants were randomly assigned to consume four beverages: a placebo containing water and caramel color, light, medium, or dark roast coffee before, during, or after consumption of a beverage containing 50 g of glucose.
In part 2 (3 weeks), participants were randomly assigned to consume four beverages: a placebo containing water and caramel color, light, medium, or dark roast coffee before, during, or after consumption of a standardized breakfast (corn flakes cereal + skim milk) containing 50 g of glucose.
In each part, fasting and postprandial glucose profiles were determined.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 19
• Age 18-64 years old with BMI less than 29 and fasting blood glucose less than 125 mg/dl.
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Age 18-64 years old with BMI less than 29 and fasting blood glucose less than 125 mg/dl.
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Weight less than 110 pounds (55 kg)
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Pre-existing health conditions, such as:
- High cholesterol
- Hypertension
- Cardiovascular disease
- Gastrointestinal motility disorders
- Hypo- or hyperthyroidism
- Anemia
- Renal disease
- Liver disease, including hepatitis B or C, cholestasis, cirrhotic liver disease, or non-alcoholic fatty liver disease
- Chronic or acute pancreatitis
- Diabetes type 1 or 2
- Insulin resistance
- Polycystic ovary syndrome
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Food allergies or intolerances to coffee/caffeine/dairy/corn-based cereals.
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Currently taking prescription medication
-
Current smoker
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Consumes more than 3 alcoholic beverages per day
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Pregnant or breastfeeding
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Not willing to take their own blood samples with finger sticks
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Changes in Blood Glucose 6 weeks Each week, fasted baseline and postprandial measurements taken out to 240 minutes
- Secondary Outcome Measures
Name Time Method Changes in Glucose Area Under the Curve 6 weeks Used glucose changes over 240 minutes to construct area under the curve
Trial Locations
- Locations (1)
Schaub Hall, Campus Box 7624
🇺🇸Raleigh, North Carolina, United States
Schaub Hall, Campus Box 7624🇺🇸Raleigh, North Carolina, United States