Renal Autotransplantation; Case Series
- Conditions
- Renal Vascular DiseaseRenal TumorNutcracker Syndrome, RenalPelvic TraumaLoin Pain-Hematuria SyndromeCongestion, Venous
- Interventions
- Procedure: Pre-Operative InformationProcedure: Intra-Operative DataOther: Post-Operative Data (up to discharge)Other: Short-Term Follow-Up Data
- Registration Number
- NCT05115812
- Lead Sponsor
- Methodist Health System
- Brief Summary
Renal autotransplantation (RAT) is a method of removing a kidney from its place of origin in a patient, repairing it, and transplanting it in another location of the body, generally the iliac fossa of the same patient.RAT is a relatively new technique; the first ever RAT procedure in the US was performed in 1963. Advances in preservation and transplantation techniques have made RAT a modality that can be utilized in complex renal diseases. RAT is indicated for conditions such as renal vascular disease, nutcracker syndrome, pelvic venous congestion, pelvic trauma, refractory stone disease and, in some cases, loin pain hematuria syndrome and conventionally unresectable renal tumors.
Irrespective of the excellent outcomes shown by RAT, the conventional open approach requires a large midline xiphoid-to-pubis or flank incision for donor nephrectomy with a second pelvic incision for renal transplantation into the iliac fossa.The current gold standard approach to RAT is a laparoscopic nephrectomy followed by open auto-transplantation. However, this approach still requires a large pelvic incision. Robotic technology enables us to perform more complex minimally invasive surgery. Gordon et al. performed and reported the first completely intracorporeal robotic RAT to repair a ureteral injury in 2014.
- Detailed Description
This is a retrospective chart review case series study of all consecutive cases in which robotic RAT was performed that meet the study inclusion and exclusion criteria. The case series will be performed starting from January 2018 until June 2021 to include all cases of robotic RAT procedures.
Perioperative and short-term clinical data will be obtained from the EMR. All the data variables will be documented in the case report forms.
Because the data will have been de-identified and is archival in nature, there will be no active subject recruitment and no patient consenting is required.
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 30
- Subject was 18 years or older at the time of the procedure
- Subject who has undergone robotic RAT irrespective of the underlying etiology.
- Subjects who do not meet the inclusion criteria
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description RAT Intra-Operative Data patients having undergone robotic-assisted RAT procedure RAT Post-Operative Data (up to discharge) patients having undergone robotic-assisted RAT procedure RAT Pre-Operative Information patients having undergone robotic-assisted RAT procedure RAT Short-Term Follow-Up Data patients having undergone robotic-assisted RAT procedure
- Primary Outcome Measures
Name Time Method Baseline patient characteristics January 2018 until June 2021 Demographics-age
Baseline patient characteristics- Hypertension January 2018 until June 2021 Medical History: hypertension
Baseline patient characteristics-indication for RAT (Renal Autotransplantation January 2018 until June 2021 Medical History: indication for RAT (Renal Autotransplantation)
Baseline patient characteristics-lesions January 2018 until June 2021 Medical History: lesions
Baseline patient characteristics- Tobacco use January 2018 until June 2021 Medical History: tobacco use
Baseline patient characteristics- Gender January 2018 until June 2021 Demographics: gender
Baseline patient characteristics-previous renal revascularization January 2018 until June 2021 Medical History: previous renal revascularization
intraoperative characteristics-Operative time January 2018 until June 2021 Operative time
Baseline patient characteristics- BMI January 2018 until June 2021 BMI, based on the American Society of Anesthesiologists status classification
Baseline patient characteristics- Diabetes January 2018 until June 2021 Medical History: diabetes
Baseline patient characteristics-cardiopulmonary disease January 2018 until June 2021 Medical History: cardiopulmonary disease
intraoperative characteristics-concomitant procedures January 2018 until June 2021 concomitant procedures
intraoperative characteristics-conversions January 2018 until June 2021 conversions
post-operative characteristics-Post-operative adverse events January 2018 until June 2021 Post-operative adverse events
intraoperative characteristics-autotransplantation technique January 2018 until June 2021 autotransplantation technique
post-operative characteristics-hospital length of stay January 2018 until June 2021 hospital length of stay
post-operative characteristics-information on enhanced recovery program January 2018 until June 2021 information on enhanced recovery program
Baseline patient characteristics-serum creatinine level January 2018 until June 2021 Medical History: serum creatinine level
short-term clinical data-Adverse events, up to 30 days post discharge Adverse events, re- admissions, re-operations related to the index procedure
intraoperative characteristics-total OR time January 2018 until June 2021 total OR time
intraoperative characteristics-transfusions January 2018 until June 2021 transfusions
intraoperative characteristics-intraoperative adverse events January 2018 until June 2021 intraoperative adverse events
post-operative characteristics-discharge status January 2018 until June 2021 discharge status
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Liver Institute of Methodist Dallas Medical Center
🇺🇸Dallas, Texas, United States