Blood Pressure or Cardiac Output - the Influence on Cerebral Perfusion During Cardiopulmonary Bypass

UMC Utrecht1 site in 1 country15 target enrollmentJanuary 2016

ConditionsCerebral Perfusion Cerebral Oxygenation Cardiopulmonary Bypass

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Cerebral Perfusion
Sponsor: UMC Utrecht
Enrollment: 15
Locations: 1
Primary Endpoint: regional cerebral oxygen saturation
Status: Completed
Last Updated: 8 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine whether cerebral blood flow and cerebral tissue oxygenation is most dependent on cardiac output or on mean arterial pressure in patients undergoing cardiac surgery with the use of cardiopulmonary bypass.

Registry

clinicaltrials.gov

Start Date

January 2016

End Date

March 17, 2017

Last Updated

8 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

UMC Utrecht

Responsible Party

Principal Investigator

Dr. B. van Zaane

MD PhD

UMC Utrecht

Eligibility Criteria

Inclusion Criteria

•Undergoing cardiopulmonary bypass for CABG a
•having an appropriate temporal bone window for reliable TCD monitoring
•needing pharmacological intervention because of hypotension before going on CPB.

Exclusion Criteria

•requiring hypothermia during surgery
•requiring emergency surgery
•contraindication for phenylephrine,
•having known brain pathology (e.g. Cerebral Vascular Accident (CVA) or increased intracranial pressure
•having a history of severe carotid artery stenosis.