ASSESS-SepsisAn exploratory cohort study to assess immune phenotypes in sepsis patients

Recruiting

• Conditions: A41.9; Sepsis, unspecified

• Registration Number: DRKS00021074
• Lead Sponsor: Klinikum rechts der Isar der TU München

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Suspected sepsis based on the current international sepsis-3 consensus definition; Suspected infection and a SOFA score >2

Exclusion Criteria

preexisting immunodeficiency, immunosuppressive therapy within the last 3 month, previous resuscitation, transfer from another ICU, active hepatitis or AIDS disease

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome is the identification of patient cluster based on their immune phenotype and their correlation with the 30d and 1year mortality.

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes are the identification of involved mechanism and signaling pathways as well as the incidence of secondary infections, length of hospitalization, readmittance rate and the development of a chronicle critical illness (CCI)