Effects of Two Physical Exercise Protocols on Cognition and Physical Performances in Oldest Old: a Randomized Controlled Trial
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Sedentary
- Sponsor
- Universidade Federal de Sao Carlos
- Enrollment
- 69
- Locations
- 1
- Primary Endpoint
- Changes from baseline in balance after 16 weeks of training and 6 weeks of detraining
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of this study is to compare the effects of different trainings on cognition and physical performances in elderly over 80 years.
Detailed Description
Purpose: To compare the effects of 16-week multicomponent and resistance trainings on cognition and physical performances related to falls in oldest old people living in community; to analyze the same variables after 6-week detraining. Method: We conducted a randomized controlled trial with 69 community elderly over 80 years, sedentary and without cognitive disorder. Participants were allocated to control, multicomponent training or resistance training group. The multicomponent group performed a protocol involving warm-up, aerobic, strength, balance and cool-down exercises. The resistance group underwent to strength exercises using six machines: leg press, chest press, calf, back extension, abdominal and rowing. The control group did not perform any intervention. The trainings had progressive intensity, lasted 16 weeks and included three 1-hour sessions per week. The participants were evaluated at baseline, at the end of 16-week training and at 6-week detraining. The assessment consisted of anamnesis, depression (Geriatric Depression Scale), cognition (Montreal cognitive assessment), dual task walking (associated to cognitive and motor tasks), balance (unipedal and tandem tests), strength of lower limbs (sit-to-stand test) and history of falls. For statistical analysis by intention to treat, we adopted a significance level of α=0.05.
Investigators
Juliana Hotta Ansai
Principal investigator
Universidade Federal de Sao Carlos
Eligibility Criteria
Inclusion Criteria
- •age between 80 and 95 years old
- •live in community
- •sedentary lifestyle
- •ability to walk without help from another person with/without aid walking
Exclusion Criteria
- •any cardiovascular or infectious comorbidity described in the absolute contraindications of the Physical Activity Readiness Medical Examination
- •Relative contraindications of cognitive, neurological and/or musculoskeletal comorbidities which make participation in protocols impossible
- •Score in mini-state examination mental below the cutoff score designated by education level.
Outcomes
Primary Outcomes
Changes from baseline in balance after 16 weeks of training and 6 weeks of detraining
Time Frame: Assessed at baseline, after 16 weeks of training and 6 weeks of detraining
Balance was assessed by unipedal test and tandem test.
Changes from baseline in dual task walking after 16 weeks of training and 6 weeks of detraining
Time Frame: Assessed at baseline, after 16 weeks of training and 6 weeks of detraining
Dual task was assessed by Timed Up and Go test with a cognitive task (speak day of week in reverse order) and motor task (carry a cup of water).
Changes from baseline in lower limbs strength after 16 weeks of training and 6 weeks of detraining
Time Frame: Assessed at baseline, after 16 weeks of training and 6 weeks of detraining
Lower limbs strength was assessed by 5 times sit-to-stand test.
Changes from baseline in cognition after 16 weeks of training and 6 weeks of detraining
Time Frame: Assessed at baseline, after 16 weeks of training and 6 weeks of detraining.
Cognition was evaluated by Montreal Cognitive Assessment.
Secondary Outcomes
- Changes from baseline in number of falls after 16 weeks of training and 6 weeks of detraining(Assessed at baseline, during 16 weeks of training and 6 weeks of detraining.)
- Changes from baseline in depression after 16 weeks of training and 6 weeks of detraining(Assessed at baseline, during 16 weeks of training and 6 weeks of detraining.)