The effect of Dexmedetomidine on the postoperative renal function in adult living donor liver transplantatio
Not Applicable
Completed
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0003220
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Both the control and dexmedetomidine groups show no significant difference in incidence of AKI. With regard to early allograft dysfunction (EAD), there was no difference in incidence of EAD in both groups. Additionally, dexmedetomidine did not decrease the incidence of delirium in liver recipients after living donor liver transplantation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 130
Inclusion Criteria
liver transplantation recipient
age betweeen 20 and 65 years
Exclusion Criteria
preoerative kidney function abnormality
Dual living donor liver transplantation
cerebral vascular disease
comblined severe cardio-pulmonary disease
chronic kidney disease
recipients who take ACEI, B-blocker or alpha2-agonist
recipinets who considered unappropriate by study conductor
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method AKI(KDIGO criteria)
- Secondary Outcome Measures
Name Time Method serial levels of blood lactate;Incidence of postoperative delirium;early allograft dysfunction;graft failure