Comparison of analgesic efficacy between Nalbuphine versus Ketamine as an adjunct to Levobupivacaine in USG guided Subcostal Transversus Abdominis Plane block in Laparoscopic Cholecystectomy.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- -To compare the duration of analgesia between the groups after administration of Subcostal TAP block.
研究概览
简要总结
This study is a randomized control, double blinded trial comparing the analgesic efficacy of nalbuphine versus ketamine as an adjunct to levobupivacaine in USG guided subcostal transversus abdominis plane block in laparoscopic cholecystectomy that is being conducted in AIIMS Raebareli. The primary outcome is to compare the duration of analgesia, the time until rescue analgesia & the amount of rescue analgesia between the two subgroups & to compare any hemodynamic parametric differences between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •All patient of ASA grade 1 and 2 aged from 18-60 years with BMI of 18.5 to 29.9 kg/m2 who are undergoing elective Laparoscopic Cholecystectomy surgery will be included.
排除标准
- •Patient refusal
- •Pregnancy
- •BMI above 30 kg/m2
- •Cerebrovascular disease
- •Systemic infection
- •Inability to understand the study protocol
- •Allergy to local anesthetics
- •Psychiatric condition that may affect patient evaluation
- •Coagulopathy
- •Infection at site of injection
- •Any Hepatic disorder
- •Any Renal disorder.
结局指标
主要结局
-To compare the duration of analgesia between the groups after administration of Subcostal TAP block.
时间窗: 24 hours
-To assess the time until 1st dose of rescue analgesia between the groups.
时间窗: 24 hours
-To quantify the amount of rescue analgesia required 24 hours post the administration of block.
时间窗: 24 hours
次要结局
- -To compare the hemodynamic parameters between the groups.(24 hours)
研究者
Dr. Sourav Acharya
AIIMS Raebareli