Antibiotics for Prevention of SSI in Obese Women Undergoing CS

Not Applicable

• Conditions: Surgical Site Infection
• Interventions: Drug: Cephalexin

• Registration Number: NCT03736187
• Lead Sponsor: Ain Shams University

Brief Summary

Effect of cephalexin plus metronidazole on SSI better than cephalexin alone in obese women undergoing CS

Detailed Description

Comparison between efficacy of cephalexin alone and cephalexin plus metronidazole on surgical site infection in obese women undergoing CS and follow up of any signs of wound infection

Study Timeline

• Study First Submitted: 2018-03-27
• Status Verified: 2018-11
• Study First Submitted QC: 2018-11-07
• Last Update Submitted: 2018-11-07
• Study First Posted: 2018-11-09
• Last Update Posted: 2018-11-09
• Study Start: 2019-04
• Primary Completion: 2019-10
• Study Completion: 2019-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 280

Inclusion Criteria

• obese women under elective CS

Exclusion Criteria

• immunodeficient women

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Cephalexin	Cephalexin	Group a will receive cephalexin 1gm before skin incision intravenous
Cephalexin &metronidazole	Cephalexin	Group b will receive cephalexin 1gm intravenous plus 1gm metronidazole rectally before skin incision

Primary Outcome Measures

Name	Time	Method
Wound infection	One week	Fever, redness, ecchymosis and tenderness