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The effect of two different drugs on post-operative well-being, nausea and vomiting in patients undergoing laparoscopic gynaecological surgery

Phase 4
Conditions
Reversal of pharmacological neuromuscular block following surgery.
Anaesthesiology - Anaesthetics
Registration Number
ACTRN12611000789965
Lead Sponsor
King Edward Memorial Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Stopped early
Sex
Female
Target Recruitment
360
Inclusion Criteria

ASA I – III physical status;
Elective or non-elective laparoscopic gynaecological surgery;
General anaesthesia with intravenous induction of anaesthesia and neuromuscular block with rocuronium;
Ability to communicate in English.

Exclusion Criteria

Anaphylaxis or hypersensitivity to any of the study drugs;
Anaesthetist preference to avoid a long acting muscle relaxant (for example, known or anticipated difficult airway);
Preoperative or perioperative conversion to open abdominal surgery;
Preoperative nausea and/or vomiting within 48 hours of surgery;
Neuromuscular disease;
Hepatic or renal dysfunction;
Personal or family history of malignant hyperpyrexia;
Long QT syndrome;
Pregnancy or breastfeeding;
Unsuitable for follow-up by phone at 24 hours (if day stay procedure).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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