COMPARISON OF OUTCOME OF INTRAVENOUS MIDAZOLAM INFUSION VERSUS INTRAVENOUS INFUSION OF SODIUM VALPROATE IN THE TREATMENT OF STATUS EPILEPTICUS IN CHILDREN AT A TERTIARY CARE HOSPITAL.
Phase 3
- Conditions
- EPILEPSY DRUGS
- Registration Number
- TCTR20231115003
- Lead Sponsor
- niversity of Health Sciences Lahore,pakistan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
All children presenting with status epilepticus with duration > 5 minutes.
Failure of first and second line antiepileptics
age group 2 to 14 years
Exclusion Criteria
All children with diagnosed muscular dystrophies on clinical examination.
severe hypotension(according to age )
severe atrial or ventricular block(on ecg)
metabolic diseases (hypoglycemia, hypocalcemia, hypomagnesemia, hyponatremia, hypenatremia, uremicencephalophaty, hepaticencephlopathy).
History of use of anticonvulsants before presenting to hospital.
Renal or Hepatic diseases on medical records and relevant investigations.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Efficacy 24 hours It will be determined in terms of complete cessation of seizures within 30 minutes of initiation of therapy and absence of seizure recurrence after completing the last dose of anticonvulsant.
- Secondary Outcome Measures
Name Time Method A NA NA