Rox Index For Predicting Outcomes Of High Flow Nasal Cannula In Covid Pneumonia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To assess the ROX index as a predictor of success of HFNC therapy for hypoxemic respiratory failure in COVID19 pneumonia
研究概览
简要总结
In patients with COVID-19 pneumonia treated for acute hypoxemic respiratory failure, there has been an increase in the utilization of non-invasive ventilation and high-flow nasal cannula (HFNC). Its increased use can be attributed to ease of use, ability to achieve higher FiO2, need for lesser expertise, use in extubation failure, and feasibility to use even in tracheostomized patients. This is especially true in countries that require more resources.1 It was also established that the risk of aerosol formation was decreased with a high-flow nasal cannula, which supports its use in COVID-19 pneumonia.2 We would like to conduct a prospective observational study to validate the ROX index as a method for predicting the failure of HFNC therapy in COVID-19 pneumonia.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients who are more than 18 yrs.
- •old with hypoxemic respiratory failure due to COVID-19 pneumonia.
排除标准
- •Patients younger than 18 years old, patients with indication for immediate intubation.
- •Patients for whom HFNC will be used for extubation failures and those with do-not-intubate order will be excluded.
- •Patients who will be electively intubated for diagnostic or therapeutic procedures (bronchoscopy, surgery) will not be included.
结局指标
主要结局
To assess the ROX index as a predictor of success of HFNC therapy for hypoxemic respiratory failure in COVID19 pneumonia
时间窗: SOFA (10) score will be recorded once a day during the first five days of HFNC therapy. We will also record the 4C COVID mortality score. (11) Clinical respiratory variables in patients 2h, 6h, 12h, 18h, and 24h after initiation of HFNC therapy will be recorded. After the first 24 hours, the same variables will be recorded once daily until HFNC withdrawal
次要结局
- To assess the relation between ROX index & ICU stay, hospital stay, & outcomes of patients(SOFA (10) score will be recorded once a day during the first five days of HFNC therapy. We will also record the 4C COVID mortality score. (11) Clinical respiratory variables in patients 2h, 6h, 12h, 18h, & 24h after initiation of HFNC therapy will be recorded. After the first 24 hours, the same variables will be recorded once daily until HFNC withdrawal)
研究者
Rajesh Chandra
Rajendra Institute of Medical Sciences