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Clinical Trials/NCT04316468
NCT04316468
Terminated
Not Applicable

Evaluation of Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation

Mayo Clinic1 site in 1 country20 target enrollmentMarch 10, 2020
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ConditionsLiver Transplant DisorderReperfusion Injury

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Liver Transplant Disorder
Sponsor
Mayo Clinic
Enrollment
20
Locations
1
Primary Endpoint
Degree of change in cardiac strain
Status
Terminated
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Researchers are trying to improve the understanding of systolic function of the heart at the time of liver reperfusion in patients undergoing orthotopic liver transplantation.

Registry
clinicaltrials.gov
Start Date
March 10, 2020
End Date
April 8, 2024
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Stephen Aniskevich, III

Principal Investigator

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

  • •Age greater than 18 years
  • •Undergoing primary orthotopic liver transplantation

Exclusion Criteria

  • •Redo orthotopic transplantation
  • •Acute or fulminant liver failure
  • •Patient with pre-existing atrial fibrillation or hypertrophic cardiomyopathy
  • •Patients with an abnormal preoperative stress test (EF \<55%, areas of prior infarct, ongoing ischemia)

Outcomes

Primary Outcomes

Degree of change in cardiac strain

Time Frame: Up to 1 hour after graft reperfusion

Evaluate the degree of change to cardiac strain using speckle tracking echocardiography

Secondary Outcomes

  • Pattern of right and left ventricular strain(Up to 5 hours from the time of surgery start)

Study Sites (1)

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