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临床试验/NCT04316468
NCT04316468终止不适用

Evaluation of Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation

Mayo Clinic1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2020年3月10日最近更新:
适应症

试验速览

阶段
不适用
状态
终止
发起方
Mayo Clinic
入组人数
20
试验地点
1
主要终点
Degree of change in cardiac strain

研究概览

简要总结

Researchers are trying to improve the understanding of systolic function of the heart at the time of liver reperfusion in patients undergoing orthotopic liver transplantation.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age greater than 18 years
  • Undergoing primary orthotopic liver transplantation

排除标准

  • Redo orthotopic transplantation
  • Acute or fulminant liver failure
  • Patient with pre-existing atrial fibrillation or hypertrophic cardiomyopathy
  • Patients with an abnormal preoperative stress test (EF <55%, areas of prior infarct, ongoing ischemia)

结局指标

主要结局

Degree of change in cardiac strain

时间窗: Up to 1 hour after graft reperfusion

Evaluate the degree of change to cardiac strain using speckle tracking echocardiography

次要结局

  • Pattern of right and left ventricular strain(Up to 5 hours from the time of surgery start)

研究者

发起方
Mayo Clinic
申办方类型
Other
责任方
Principal Investigator
主要研究者

Stephen Aniskevich, III

Principal Investigator

Mayo Clinic

研究点 (1)

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