NL-OMON40554
Completed
Not Applicable
Advanced PET and MRI techniques for improved therapy response assessment in diffuse large B-cell lymphoma / follicular lymphoma grade 3B - MITRAL; molecular imaging techniques for response assessment in lymphoma
niversitair Medisch Centrum Utrecht0 sites110 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diffuse large B-cell lymphoma / follicular lymphoma grade 3B
- Sponsor
- niversitair Medisch Centrum Utrecht
- Enrollment
- 110
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Male or female patients
- •\- Age: 18 years and older
- •\- Histologically proven diffuse large B\-cell lymphoma / Follicular lymphoma grade 3B
- •\- Patients scheduled to undergo front\-line R\-CHOP 21 therapy
- •\- Patients must be capable of giving written informed consent and the consent must have been obtained before the study\-related procedures
Exclusion Criteria
- •\- General contraindications for MRI (including cardiac pacemakers and claustrophobia). \- Previous malignancy. However, subjects who have been free of malignancy for at least 5 years, or have a history of completely resected non\-melanoma skin cancer, or successfully treated in situ carcinoma are eligible. \- Diffuse large B\-cell lymphoma / follicular lymphoma grade 3B central nervous system involvement. \- Diffuse large B\-cell lymphoma / follicular lymphoma grade 3B stage I disease. \- HIV positivity (de novo or active) \- Pregnant or lactating women. \- Therapy has already started before pretreatment dual\-time point 18F\-FDG PET and DWI scans could be performed.
Outcomes
Primary Outcomes
Not specified
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