Randomized controlled clinical trial to evaluate the efficacy of Ashwatthadi Churna in the management of Shayyamutrata (nocturnal enuresis) in children.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
In Shayyamutrata, the vitiated doshas primarily include Vata (Apana Vayu), Pitta (Pachaka pitta), and Kapha (Tarpaka kapha), along with the aggravation of the mental dosha, Tamas. And the Rasa dhatu (Ambu) is the affected dushya.
The vitiation of Mutravaha and Manovaha srotas manifests as increased frequency of urine at night, which is untimely and disruptive to normal sleep patterns. This disruption indicates an imbalance in the Mutravaha and Manovaha strotas according to Ayurvedic principles.
Hetu:
A. Manasika Hetu=
1.Chinta
2.Bhaya
3.Krodha
4.Kautumbic Kalaha
B. Sharirika Hetu=
1.Krimi
2.Mutrashaya Shithilata
3.Niruddhaprakasha
4.Jananendriya Sankraman
5.Koshthabaddhata
Considering pathology of the Shayyamutrata, treatment should be planned in a multidimensional approach.
Counselling, Medhya drugs, Pramehaghna drugs, Dhatushaithilyahara drugs, krumighna drugs , kaphaahar drugs, vatanulomak drugs and Mutrasangrahniya drugs in combination may form a comprehensive protocol for management of Shayyamutrata.
The enuresis is defined as the voiding of urine in bed or in clothes (unintentional or deliberately ) as manifested by either a frequency of at least twice a week for at least 3 consecutive months or presence of clinically significant distress or impairment in social, academic (occupational), or other important areas of functioning when the child of about 5 years of age or more.
The prevalence of Nocturnal Enuresis in Chhatrapati Sambhajinagar district among children of age 5 to 10 years was 10.91% in which 06.94% were males and 03.97% females. Withregard to severity 55% children were found to be in moderate category while 09% belonged to severe category of Nocturnal Enuresis.
In the modern medicine, management of Nocturnal Enuresis consist of behavioral modifications, bladder training, alarm therapy, diet management and use of drugs like desmopressin, anticholinergic agents, and tricyclic antidepressants like imipramine which having rare but serious adverse effect like cardiac arrhythmias. But none of the treatments till now can be completely relied upon. And relapse rates are high after stopping the medication.
It’s true that modern medicine hasn’t found a sure cure for Bedwetting, and some prescribed drugs may have side effects and limitations. While Ayurvedic treatments have shown promise in some studies, more research is needed for a conclusive understanding. Ultimately, a safe and effective cure for Bedwetting is still awaited, emphasizing the need for continued research and innovation in this area.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 5.00 Year(s) 至 12.00 Year(s)（—）
- 性别
- All
入选标准
- •Children complaining of Shayyamutrata i.e. Nocturnal enuresis between 5 to 12 years age group will be selected.
- •Repeated voiding of urine in the bed or clothes at night ,2 or more than 2 times in a week, for at least 3 months.
- •Patients irrespective of their sex, religion and socio-economiccal status.
- •Patients agreed for treatment and with informed consent.
排除标准
- •Systemic disorders like Diabetes Mellitus and Diabetes Insipidus.
- •Congenital anomalies or with anatomical defect in genital urinary system and UTI.
- •Neurodevelopment disorders like Mental Retardation, Cerebral Palsy, Spina bifida and seizure disorders.
- •Any Other systemic illness.
- •Any Obstruction in Lower Urinary Tract Like Posterior urethral valve stenosis, distal urethral stenosis.
研究者
Dr Shilpa Mohan Korekar
Chhatrapati Shahu Maharaj Shikshan Sanstha Ayurved Mahavidyalaya, Aurangabad