Clinical study on prevention and treatment of radiation acute oral mucositis in patients with nasopharyngeal carcinoma by self-prepared Chinese herbal compound preparation

Affiliated Hospital of Chengdu University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

暂无简介。

•1. Patients with locally advanced nasopharyngeal carcinoma diagnosed by pathology and UICC/AJCC TNM staging of stage III and stage A in the 8th edition;
•2. Has indications for radical concurrent radiotherapy and chemotherapy, and is scheduled to receive (IMRT technique for radiotherapy, platinum-containing regimen for chemotherapy), and has received radiotherapy for the first time, and has not received surgical treatment;
•3. Kanofsky Performance Status (KPS) score >= 70;
•4. Blood routine, normal liver and kidney function, and good blood glucose control in diabetic patients (fasting blood glucose 3.9-7.2mmol/L, blood glucose 2 hours after meal <= 10.0mmol/L, HbA1c < 7%);
•5. Expected survival of at least 6 months;
•6. Age between 18 and 70 years old, male or female;
•7. Signing the informed consent.

•1. Pregnant women, lactating women, and women of childbearing age who were unable to obtain effective contraception during the trial;
•2. Other established oral mucosal diseases and no previous history of salivary gland diseases;
•3. Patients with recurrent or residual nasopharyngeal carcinoma;
•4. Complicated with serious heart, liver, kidney, hematopoietic system and nervous system diseases, diabetes mellitus with unsatisfactory blood glucose control and mental disorders;
•5. Patients with other malignant tumors;
•6. People who are known or suspected to be allergic to the drugs in this study;
•7. Other circumstances that the researcher considers not suitable for the study.

发起方

Affiliated Hospital of Chengdu University of Traditional Chinese Medicine