Skip to main content
MedPathMedPath Home
Clinical Trials/NCT01213784
NCT01213784
Completed
Phase 2

Optimized Glycemic Control in Type 2 Diabetics With Heart Failure:"Effect on Left Ventricular Function and Skeletal Muscle"

University of Aarhus1 site in 1 country40 target enrollmentSeptember 2010
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsType 2 DiabetesHeart Failure

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Type 2 Diabetes
Sponsor
University of Aarhus
Enrollment
40
Locations
1
Primary Endpoint
Left ventricular function
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The investigators wish to investigate wether a more strict diabetic control improves cardiac function, muscle strength, exercise capacity and decreases symptoms.

The investigators hypothesis is that improving the glycemic control in suboptimized diabetics with heart failure will improve cardiac performance, muscle strength, exercise capacity and decrease symptoms.

Registry
clinicaltrials.gov
Start Date
September 2010
End Date
November 2012
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •Ejection fraction =\<45%
  • •Hba1c =\>7,5%
  • •In anticongestive treatment
  • •NYHA class 2-4

Exclusion Criteria

  • •Severe angina (CCS 3-4)
  • •Hemodynamic significant heart valve disease
  • •Congenital heart disease
  • •Pregnancy

Outcomes

Primary Outcomes

Left ventricular function

Time Frame: 4 month

Left ventricular function will be evaluated using echocardiografi measuring: - 2D Ejection fraction (using an ultrasound agent), global and regional tissue velocity, Strain / strain rate - all measures done during rest and dobutamin stress test.

Secondary Outcomes

  • 6-minutes hall walk test(4 month)
  • Exercise capacity and peak oxygen consumption(4 month)
  • Muscle strength and mass(4 month)
  • hormonal and metabolic profile(4 month)

Study Sites (1)

Loading locations...

Similar Trials

Not yet recruiting
Not Applicable
Effect the Glycemic Control on Cardiac FunctionCardiac FunctionGlycemic Control
NCT06761820Assiut University200
Completed
Not Applicable
How Improvement in Control of Diabetes Influences the Production of a Hormone Produced in the Gut Which Improves the Release and Action of Insulin.Type 2 Diabetes Mellitus
NCT00747383The Royal Bournemouth Hospital74
Completed
Not Applicable
DARE: Diabetes in cArdiac REhabilitationType 2 Diabetes MellitusCoronary Artery Disease
NCT00354237Centre Hospitalier Universitaire Dijon60
Unknown
Not Applicable
Can Enhanced Glycemic Control in Type II Diabetics Improve Myocardial Protection During Coronary Artery Bypass Grafting?Type 2 Diabetes
NCT00899483University Hospital Birmingham100
Completed
Phase 3
A Study to Evaluate Combining Metformin With Muraglitazar or Pioglitazone in Type 2 DiabeticsType 2 Diabetes
NCT00240370Bristol-Myers Squibb1,159