NCT00747383已完成不适用
Influence of Improving Glycaemic Control on Glucagon-Like-Peptide-1 Response to an Oral Glucose Load. Comparison of Sulphonylurea With DPP-4 Inhibition.
The Royal Bournemouth Hospital1 个研究点 分布在 1 个国家目标入组 74 人开始时间: 2008年9月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 74
- 试验地点
- 1
- 主要终点
- Comparison of GLP-1 response at baseline and after 3 months treatment of both groups.
研究概览
简要总结
The study is aimed at Type 2 Diabetics who are taking Metformin, but whose Diabetes remains poorly controlled. There are two additional medications already in use, Glimepiride and Sitagliptin will be compared to assess levels of improvement in Diabetes control.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diabetes Mellitus
- •Currently on Metformin but poor glycaemic control,
排除标准
- •Under 18 years of age
研究组 & 干预措施
1
Active Comparator
干预措施: Glimepiride (Drug)
2
Active Comparator
干预措施: Sitagliptin (Drug)
结局指标
主要结局
Comparison of GLP-1 response at baseline and after 3 months treatment of both groups.
时间窗: 2 years
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
The Guardcontrol Trial: Study to Assess if Type 1 Diabetics Can Improve Using the Real-time Values of Guardian RTDiabetes MellitusNCT00111228Medtronic Diabetes162
已完成
不适用
Continuous Glucose Monitoring & Management In Type 2 Diabetes (T2D)Diabetes Mellitus, Type 2NCT03620357DexCom, Inc.72
已完成
不适用
Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes SplicingType 2 DiabetesNCT01349387Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète25
已完成
3 期
A Study to Evaluate Combining Metformin With Muraglitazar or Pioglitazone in Type 2 DiabeticsType 2 DiabetesNCT00240370Bristol-Myers Squibb1,159
已完成
2 期
Optimized Glycemic Control in Heart Failure Patients With DM2:"Effect on Left Ventricular Function and Skeletal Muscle"Heart FailureType 2 DiabetesNCT01213784University of Aarhus40