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Clinical Trials/NCT00747383
NCT00747383
Completed
Not Applicable

Influence of Improving Glycaemic Control on Glucagon-Like-Peptide-1 Response to an Oral Glucose Load. Comparison of Sulphonylurea With DPP-4 Inhibition.

The Royal Bournemouth Hospital1 site in 1 country74 target enrollmentSeptember 2008
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ConditionsType 2 Diabetes Mellitus
InterventionsGlimepirideSitagliptin
DrugsGlimepirideSitagliptin

Overview

Phase
Not Applicable
Intervention
Glimepiride
Conditions
Type 2 Diabetes Mellitus
Sponsor
The Royal Bournemouth Hospital
Enrollment
74
Locations
1
Primary Endpoint
Comparison of GLP-1 response at baseline and after 3 months treatment of both groups.
Status
Completed
Last Updated
13 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSitesSimilar Trials

Overview

Brief Summary

The study is aimed at Type 2 Diabetics who are taking Metformin, but whose Diabetes remains poorly controlled. There are two additional medications already in use, Glimepiride and Sitagliptin will be compared to assess levels of improvement in Diabetes control.

Registry
clinicaltrials.gov
Start Date
September 2008
End Date
September 2010
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
The Royal Bournemouth Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •Diabetes Mellitus
  • •Currently on Metformin but poor glycaemic control,

Exclusion Criteria

  • •Under 18 years of age

Arms & Interventions

1

Intervention: Glimepiride

2

Intervention: Sitagliptin

Outcomes

Primary Outcomes

Comparison of GLP-1 response at baseline and after 3 months treatment of both groups.

Time Frame: 2 years

Study Sites (1)

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