Use of PRF in Treatment of Dry Socket.

Not Applicable

• Conditions: Alveolar Osteitis
• Interventions: Procedure: PRF application; Drug: Nipas application

• Registration Number: NCT04476121
• Lead Sponsor: Medical University of Lodz

Brief Summary

The aim of the study is to evaluate the influence of PRF application in case of alveolar osteitis.

Detailed Description

The main objective was to compare the effects of using two different methods in the treatment of dry socket (alveolar osteitis), which is a postoperative complication of dental extraction. The first was Nipas, applied, if dry socket was diagnosed following a tooth extraction. In case of subsequent extraction of homonymous tooth and reoccurrence of dry socket, patients were treated with application of PRF.

Study Timeline

• Study Start: 2019-01-01
• Status Verified: 2020-06
• Study First Submitted: 2020-07-15
• Study First Submitted QC: 2020-07-15
• Study First Posted: 2020-07-17
• Last Update Submitted: 2021-04-23
• Last Update Posted: 2021-04-26
• Primary Completion: 2021-07-01
• Study Completion: 2021-07-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• no known medical history of abnormal platelet counts,
• patients with symmetric teeth qualified for extraction,

Exclusion Criteria

• patients treated previously for existing dry socket,
• patients allergic to acetylsalicylic acid ,
• systemic diseases,
• pregnancy,
• lactation,
• drugs known to affect the number or function of platelets,
• abnormal platelet counts,

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
PRF application	PRF application	Patients with alveolar osteitis in which PRF application was performed.
Aspirin application	Nipas application	Patients with alveolar osteitis in which Nipas was used.

Primary Outcome Measures

Name	Time	Method
Influence of treatment on bacteria levels in wounds	24 hours	The second part of the study was dedicated to analyzing the number of bacteria in tooth extraction wounds.
Intensity of pain vs. PRF and Nipas application	24 hours	In order to evaluate the relationship between intensity of pain after application of PRF and Nipas, Numeric Rating Scale pain scale is used. NRS is a horizontal line with an eleven point numeric range. It is labeled from zero to ten, with zero being an example of someone with no pain and ten being the worst pain possible.; The higher score means worse outcome in case of present study.

Trial Locations

Locations (1)

Department of Oral Surgery; 🇵🇱 Lodz, Poland