Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and Hypothyroidism

Completed

• Conditions: Hyperthyroidism; Hypothyroidism

• Registration Number: NCT02005250
• Lead Sponsor: Steen Bonnema

Brief Summary

The aim to evaluate the bone structure by Dexa-scan, extreme CT and bone markers before and one year after treatment for a thyroid functional disorder

Detailed Description

The aim to evaluate the bone structure by Dexa-scan, extreme CT and bone markers before and one year after treatment for a thyroid functional disorder. Women with hyper- og hypothyroidism are included and undergo usual treatment. Patients are stratified into 10 different groups.

Study Timeline

• Study Start: 2012-02
• Study First Submitted: 2013-12-03
• Study First Submitted QC: 2013-12-03
• Study First Posted: 2013-12-09
• Primary Completion: 2016-10
• Study Completion: 2020-01-01
• Results First Submitted: 2020-03-06
• Status Verified: 2020-04
• Results First Submitted QC: 2020-04-09
• Last Update Submitted: 2020-04-09
• Results First Posted: 2020-04-13
• Last Update Posted: 2020-04-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 93

Inclusion Criteria

informed consent, female sex, age 20-85 years, indication for treatment of the thyroid disorder,

Exclusion Criteria

pregnancy, renal insufficiency, known osteoporosis, other disease that may affect bone metabolism, medication which affects bone metabolism, T-score below -3.5, thyroidea ophthalmopathy with indication for steroids,

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Thyroid Extreme CT	one year	Bone cortical thickness in the radius measured by high-resolution peripheral quantitative CT, in newly diagnosed thyroid disorder, before and after treatment aimed to obtain euthyroidism

Trial Locations

Locations (1)

Odense University Hospital; 🇩🇰 Odense, Denmark