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临床试验/NCT02005250
NCT02005250已完成不适用

Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and Hypothyroidism

Steen Bonnema1 个研究点 分布在 1 个国家目标入组 93 人开始时间: 2012年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
93
试验地点
1
主要终点
Thyroid Extreme CT

研究概览

简要总结

The aim to evaluate the bone structure by Dexa-scan, extreme CT and bone markers before and one year after treatment for a thyroid functional disorder

详细描述

The aim to evaluate the bone structure by Dexa-scan, extreme CT and bone markers before and one year after treatment for a thyroid functional disorder. Women with hyper- og hypothyroidism are included and undergo usual treatment. Patients are stratified into 10 different groups.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • informed consent, female sex, age 20-85 years, indication for treatment of the thyroid disorder,

排除标准

  • pregnancy, renal insufficiency, known osteoporosis, other disease that may affect bone metabolism, medication which affects bone metabolism, T-score below -3.5, thyroidea ophthalmopathy with indication for steroids,

结局指标

主要结局

Thyroid Extreme CT

时间窗: one year

Bone cortical thickness in the radius measured by high-resolution peripheral quantitative CT, in newly diagnosed thyroid disorder, before and after treatment aimed to obtain euthyroidism

次要结局

未报告次要终点

研究者

发起方
Steen Bonnema
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Steen Bonnema

Consultant, phd, DMsc

Odense University Hospital

研究点 (1)

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