Analysis of the Persistence, Reservoir and HIV Latency

Not yet recruiting

• Conditions: HIV Infected Individuals; Informed Consent

• Registration Number: NCT05752318
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

The APRIL study aims at analyzing HIV reservoirs, latency and persistence on antiretroviral therapy. It enrolls HIV-infected adults providing blood samples of which peripheral blood mononuclear cells are stored. The frequency, phenotype and inducibility of HIV-infected cells are then analyzed. These parameters may vary across the different clinical and therapeutic settings.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-01
• Study First Submitted: 2023-01-12
• Study Start: 2023-02-27
• Study First Submitted QC: 2023-02-28
• Last Update Submitted: 2023-02-28
• Study First Posted: 2023-03-02
• Last Update Posted: 2023-03-02
• Primary Completion: 2027-01-25
• Study Completion: 2027-02-25

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• HIV-infection
• Adults (>18 years)
• Social insurance
• Informed consent

Exclusion Criteria

• HIV-uninfected
• <18 years
• Lack of social insurance
• Lack or withdraw of consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HIV-Flow	1 day