The Respiratory and Hemodynamic Effects of Alveolar Recruitment during and after Liver Transplantation: RCT

Not Applicable

• Conditions: Digestive System; End stage liver disease; Anaesthesia

• Registration Number: PACTR201811462663708
• Lead Sponsor: ational Liver Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-11-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 57

Inclusion Criteria

Model of end stage liver disease (MELD) score less than 24.
Elective adult living donor liver transplant recipient patients with chronic liver disease.

Exclusion Criteria

-Patients with pre-existing significant pulmonary disease with abnormalities in spirometry, previous lung surgery, home oxygen therapy and signi?cant cardiac dysfunction.
-Acute liver failure and redo-transplant.
-Patients with pulmonary hypertension.
-Body-mass index higher than 40 kg/m²
-Unwilling to participate in the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Arterial oxygen tension (PaO2) ;The ratio of PaO2 to the fraction inspired oxygen (PaO2/FIO2)

Secondary Outcome Measures

Name	Time	Method
incidence of postoperative pulmonary complications (pleural effusion –pneumonia-respiratory failure)