Comparison of ultrasound guided External Oblique Intercostal plane block and Transversus Abdominis plane block for postoperative analgesia in patients undergoing upper abdominal surgery under general anaesthesia
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Total 24 hour injection tramadol consumption
研究概览
简要总结
After preanaesthetic evaluation and obtaining written informed consent, patients will
be randomised by computer generated numbers into two groups.
Group E: Patients receiving External Oblique Intercostal Plane Block.
Group T: Patients receiving Transversus Abdominis Plane Block.
Patients in each group will receive 20 mL 0.125% bupivacaine with additive inj Fentanyl
2mcg/kg postoperatively. The patient will be shifted to operation theatre. Standard monitors
will be attached (noninvasive B.P, ECG, pulse oximetry, temperature probe) to record the
baseline vitals which will be monitored all through the procedure.
After obtaining wide bore intravenous access. Following injection Midaz 1.0 mg i/v,
injection Fentanyl 2.0 mcg/kg i.v., and injection propofol 2.0 mg/kg; check ventilation will be
done, and muscle relaxation will be attained using injection Vecuronium 0.1 mg/kg followed
by tracheal intubation with appropriate size endotracheal tube and put on mechanical
ventilation. Anaesthesia will be maintained with air, oxygen and sevoflurane with a MAC of
1-1.2
Vital signs ; HR, SBP, DBP, MAP, SpO2 will be recorded.
Injection fentanyl 1.0 mcg/kg will be administered if HR or MAP rise more than 20% of
baseline
Patients will receive injection paracetamol 15mg/kg after induction of anesthesia and 6
hourly till 24 hours after surgery
At the end of surgery respective ultrasound guided block will be given by an experienced
anaesthesiologist according to the study group allotted.
Injection ondansetron 0.1 mg/kg will be administered, and patient will be reversed
with injection neostigmine (0.05mg/kg) and injection glycopyrollate (0.01mg/kg).
Postoperatively HR, SBP, DBP, MAP and SpO2 heart rate, systolic blood pressure, diastolic
blood pressure, mean arterial pressure, SpO2, and NRS score (on scale of 1-10) will be
recorded at 5 min, 30 min, 60 min, 6hr, 12hr and 24 hr postoperatively by the anaesthesiologist
blinded to the group allotted.
Patients will be administered injection tramadol 50mg if NRS score is more than or equal to 4
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade 1 and 2 .
- •Elective upper abdominal surgeries .
排除标准
- •Known allergy to local anaesthetics.
- •Infection at injection site.
- •Patients undergoing chronic analgesia therapy.
- •Laparoscopic surgeries.
- •Patients with BMI more than 30.
结局指标
主要结局
Total 24 hour injection tramadol consumption
时间窗: 5 minutes, 30 minutes, 1 hour, 6 hours, 12 hours, and 24 hours after intervention.
次要结局
- Time to first rescue analgesia postoperatively.(Patient satisfaction based on Likert scale (0-5).)
研究者
Naoshad Baqir
ABVIMS and Dr. Ram Manohar Lohia Hospital, New Delhi