Exercise-Induced Changes in Serum Oncostatin M Levels in Recreationally Active Males

Not Applicable

Completed

• Conditions: The Aim of This Study is to Evaluate the Effects of Acute Exercise on Serum Oncostatin M Levels in Healthy, Recreationally Active Males

• Registration Number: NCT07195630
• Lead Sponsor: Hacettepe University

Brief Summary

The aim of this study was to compare the effects of workload-matched acute moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) on serum OSM levels on a cycle ergometer in recreationally active, healthy men. Fifteen participants participated in both MICE and HIIE sessions. The HIIE session consisted of 10 x 1 min intervals at 90% of maximal oxygen uptake (VO2max) separated by a 75-second active recovery period at 60 W, whereas the MICE session consisted of a \~21 min exercise session at 55% of VO2max. Blood samples were collected before (Pre) and immediately after (Post) acute MICE and HIIE sessions. Serum OSM levels were measured by the ELISA method.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-01
• Primary Completion: 2024-08-01
• Study Completion: 2024-09-20
• Status Verified: 2025-09
• Study First Submitted: 2025-09-13
• Study First Submitted QC: 2025-09-19
• Last Update Submitted: 2025-09-19
• Study First Posted: 2025-09-26
• Last Update Posted: 2025-09-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 15

Inclusion Criteria

• Engaged in regular exercise/training in the last 6 months,
• 18-30 years of age,
• Body mass index (BMI) in the range of 18.5-24.9 kg/m².

Exclusion Criteria

• Having a chronic disease that limits exercise,
• Smoking,
• Using any medication or supplement that may affect metabolism.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Change from Pre- to Post-Exercise Levels of Oncostatin M	From baseline assessment of blood samples at pre-exercise to the assessment of blood sample analysis at the end of the post-exercise.	Serum samples were collected at pre- and post-exercise time points, and serum oncostatin M levels were measured using a commercial ELISA kit

Trial Locations

Locations (1)

Hacettepe University; Ankara, Çankaya, Turkey (Türkiye)