Evaluation of Nasal Non Invasive Ventilation Modalities in Management of Neonates With Respiratory Distress Using Lung Ultrasound
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Duration of non-Invasive ventilation (NIV)
研究概览
简要总结
This study aims to evaluate the effect of non-invasive ventilation (nIPPV)
, (nCPAP), and nasal high flow cannula (NHFC) as a primary mode of ventilation in preterm neonates <37 gestational week with moderate to severe RD using LUS as regard: I. Primary outcomes: Duration of non-Invasive ventilation. II. Secondary outcomes: Evaluation LUS over the 1 st 7 days of life or weaning from ventilation. Need for intubation and invasive ventilation. Duration of respiratory support. Need for surfactant. Oxygen saturation index and oxygen index. Broncho-pulmonary dysplasia; grade. Duration of hospital stay
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 1 Hour 至 24 Hours（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Preterm <37 wk. gestational age admitted to the NICU with spontaneous breathing and clinical manifestations of RD (tachypnea, nasal flaring, intercostal and subcostal retraction and or grunting).
排除标准
- •Obvious major congenital abnormalities.
- •Any of the baby intubated for resuscitation or for other reasons.
- •Neonates need invasive mechanical ventilation.
- •Pulmonary hemorrhage.
- •Severe cardiovascular instability.
- •Cardiopulmonary arrest needing prolonged resuscitation.
- •Birth asphyxia (one-minute Apgar score ≤ 3).
- •Major cardiac diseases (not including patent ductus arteriosus).
结局指标
主要结局
Duration of non-Invasive ventilation (NIV)
时间窗: First two weeks of life.
Describe the days of non-invasive ventilation , described in days number.
次要结局
- Oxygen saturation index (OSI).(first one weeks of life.)
研究者
Marwa Mohamed Farag
Assistant professor
Alexandria University