Contributions to diagnosis and management of dry eye diseases: a systematic and stepwise approach.

• Conditions: Dry eye diseases; tearfilm disorders; 10021877

• Registration Number: NL-OMON41930
• Lead Sponsor: Oogheelkundig Medisch Centrum Zaandam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 370

Inclusion Criteria

Inclusion criteria persons without dry eyes: age > 18 years, never have symptoms of dry eyes (scored at the Mcmonnies questionnaire) , Osmolarity < 308.
Inclusion criteria persons with dry eyes: age > 18 years, symptoms of dry eyes (scored on the Mcmonnies questionnairre), Osmolarity > 308.

Exclusion Criteria

Exclusion criteria for persons with and without dry eye symptoms: eye surgery, including refractive and plastiv surgery, herpes simpex infections, allergic constituion, antiglaucoma therapy, contact lens wearers, visual acuity < 0.1, chemotherapy treatment.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The evaporation rate, and the dew point, Sialic acid concentration, number of<br /><br>goblet cells.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>subjective extent to which the patient experiences symptoms (McMonnies<br /><br>questionnaire, VAS scale), the Schirmer test. </p><br>