Affect of Dose Rate on UVR Induced Skin Erythema
Not Applicable
- Conditions
- Erythema
- Registration Number
- NCT00785187
- Lead Sponsor
- Goldenhersh, Michael, M.D.
- Brief Summary
Purpose of study: Evaluation of the affect of dose rate on UVR induced skin erythema.
Study design: A single-center, prospective, randomized, crossover, open study.
Number of patients: 20-40
Patient population: Healthy volunteers
Control: Different sites on patients body
Procedure duration: Total 3-5 hours (4 visits)
Duration of follow up: 4 days
Duration of study: Up to 6 months
Primary objectives: To examine the difference in erythemal response as a function of dose rate, and to assess the total amount of energy that is theoretically transmitted through a sunscreen within the range of SPF 2-10.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Fitzpatrick Skin types I-III.
- Age 18-60.
- Absence of obvious sun damage on the volar side of the forearm or other exposure sites.
- Absence of exposure of the arms or other exposure sites to sunlight for two weeks prior to the experiment.
Exclusion Criteria
- History of skin cancer.
- Multiple nevi or atypical nevi on the forearm.
- Signs of sun damage on the volar side of the forearm or other exposure sites.
- Mentally incompetent.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method To examine the difference in erythemal response as a function of dose rate, and to assess the total amount of energy that is theoretically transmitted through a sunscreen within the range of SPF 2-10 end of study
- Secondary Outcome Measures
Name Time Method