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Clinical Trials/DRKS00014695
DRKS00014695
Completed
N/A

Contribution of respiratory muscle strength and right ventricular pump function to exercise intolerance in patients with precapillary pulmonary hypertension

Institut für Schlafmedizin und neuromuskuläre Erkrankungen Universitätsklinikum Münster0 sites86 target enrollmentMay 14, 2018
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ConditionsI27.0I27.20Primary pulmonary hypertension

Overview

Phase
N/A
Intervention
Not specified
Conditions
I27.0
Sponsor
Institut für Schlafmedizin und neuromuskuläre Erkrankungen Universitätsklinikum Münster
Enrollment
86
Status
Completed
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 14, 2018
End Date
TBD
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Institut für Schlafmedizin und neuromuskuläre Erkrankungen Universitätsklinikum Münster

Eligibility Criteria

Inclusion Criteria

  • •a. Age \> 18 years (no age limit)
  • •b. able to consent
  • •c. Diagnosis of Nizza class I or IV precapillary pumonary Hypertension according to the most recent Guidelines of the European Society of Cardiology (ESC); \>12 weeks since the diagnosis of PH has been made; no hospitalisation for HF in the last 4 weeks; optimal medical therapy in accordance with the most recent Guidelines of the European Society of Cardiology (ESC) with no change in medication in the last 4 weeks and combination therapy for PAH \-where there was no treatment with combination therapy in PAH patients then the reason must be documented

Exclusion Criteria

  • •\- secondary (postcapillary) pulmonary hypertension (mean pulmonary arterial hypertension \> 25 mmHg; PCWP \>15 mmHg)
  • •\- other severe internistic pre\-existing conditions, especially insulin\-dependent diabetes or severe renal impairment
  • •\- severe neurological pre\-existing conditions such as stroke, especially brainstem infarction
  • •\- intake of opioids
  • •\- severe psychiatric pre\-existing conditions
  • •\- contraindications to (cardiac) magnetic resonance imaging (MRI)

Outcomes

Primary Outcomes

Not specified

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