A comparative study between the effects two medicines, oral clonidine and pregabalin on pain relief after surgery under spinal anaesthesia.

Not yet recruiting

• Conditions: Administration,

• Registration Number: CTRI/2019/04/018641
• Lead Sponsor: Indira Gandhi Institute of Medical Sciences

Brief Summary

We plan to study the effect of oral clonidine and oral pregabalin administered before spinal anaesthesia and to see their effect on post operative analgesia upto 24 hours after surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-04-17
• Last Update Posted: 2019-12-04

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

ASA physical status I and II Patients able to comprehend and participate Patients in whom oral clonidine and pregabalin is indicated for induction analgesia.

Exclusion Criteria

• Patients refusal to participate Contraindications to use of oral clonidine and pregabalin.
• Patients with known sensitivity to clonidine and pregabalin Patients with deranged renal function Contraindication of spinal anaesthesia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the effect of oral clonidine and pregabalin on post-operative analgesia under spinal anaesthesia	From administration of drug to upto 24 hours of surgery

Secondary Outcome Measures

Name	Time	Method
To evaluate the effect of oral clonidine and pregabalin on incidence of hypotension and bradycardia for surgeries under spinal anaesthesia	From administration of drug to upto 24 hours of surgery

Trial Locations

Locations (1)

Indira Gandhi Institute of Medical Sciences; 🇮🇳 Patna, BIHAR, India

Indira Gandhi Institute of Medical Sciences

🇮🇳Patna, BIHAR, India

Dr Navin Kumar

Principal investigator

8210442195

navinnav06@gmail.com