PReventive effect Of left bundle branch area pacing versus righT vEntricular paCing on all cause deaTh, heart failure progression, and ventricular dysSYNChrony in patients with substantial ventricular pacing (PROTECT-SYNC): Multicenter Prospective observational cohort study
Not Applicable
Recruiting
- Conditions
- Diseases of the circulatory system
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 450
Inclusion Criteria
1. At least 19 years old and willing and capable to give informed consent
2. Patients who is willing and able to comply with the prescribed follow-up tests and schedule of evaluations.
3 Scheduled to receive a pacemaker implant
4. Substantial percentage of V pacing rate (>40%) is anticipated
Exclusion Criteria
1. Incapacitated or unable to read or write
2. Patient who is an indication of ICD or CRT
3. History of prosthetic valve surgery on tricuspid valve
4. Prior myocardial infarction including ventricular septum
5. Life expectancy < 12 months due to any condition
6. Unavailable for at least 24 months of follow-up visits
7. Pregnant or breastfeeding at the time of signing consent
8. Prior Heart transplant surgery
9. Persistent Left Superior Vena Cava (PLSVC)
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method composite of all-cause death, heart failure hospitalization, and an upgrade to cardiac resynchronization therapy
- Secondary Outcome Measures
Name Time Method all cause mortality;Cardiovascular mortality;Heart failure hospitalization;success rate of LBBAP implantation;LBB capture failure;Short-term procedure and Device related complications;Long-term procedure and Device related complications;Rate of LV systolic dysfunction;Changes in cardiopulmonary exercise test parameters;Incidental atrial fibrillation