Comparison of left bundle branch area pacing and minimized ventricular pacing in patients with sinus nodedysfunction and atrioventricular dromotropathy: A Multicenter, randomized controlled, clinical trial
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0009577
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 130
>18 years old
- Sinus node dysfunction with symptoms
- Atrioventricular conduction delay (PR interval > 180ms)
- Subject was unable to provide written informed consent or participate in long-term follow-up.
- Permanent atrial fibrillation
- Persistent advanced atrioventricular conduction disturbance (Mobitz type II or 3rd degree) with >40% of expected ventricular pacing burden
- Mechanical tricuspid valve
- Ventricular septal defect or scar
- Left ventricular ejection fraction < 35% who indicated cardiac resynchronization therapy
- Previous heart transplantation
- Pregnant and/or lactating women.
- Life expectancy <2 year
- Patients who are actively participating in another drug or device investigational study, which have not completed the primary endpoint follow-up period
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method death;heart failure;new onset permanent atrial fibrillation
- Secondary Outcome Measures
Name Time Method death rate;stroke;cardiac re-hospitalization;re-implant;atrial fibrillation;atrial fibrillation;atrial fibrillation;Procedure time;LBBAP success rate;LV ejection fraction;LV dimension;LA dimension;Valvular heart disease;E/e’ value;sensing value, pacing threshold, impedance