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Role of Exercise in Diastolic Heart Failure

Not Applicable
Completed
Conditions
Heart Failure With Preserved Ejection Fraction
Diastolic Heart Failure
Registration Number
NCT01047631
Lead Sponsor
University of Michigan
Brief Summary

Diastolic heart failure is now being recognized as a key form of heart failure in older people. The focus of this research is to study ways to improve and maintain physical activity and functioning. This knowledge may improve the health and well-being in people with diastolic heart failure.

Detailed Description

The purpose of this project is to better understand how endurance and fatigue relate to performing daily activities and how we might better improve endurance and reduce fatigue through an exercise program.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Age 60 and over
  • Evidence of diastolic dysfunction on echocardiogram
  • Normal Left Ventricular Function (LVEF≥50%)
  • Heart Failure-NYHA Class II/III
  • Able and willing to participate in exercise program
  • Able to come to Ann Arbor Michigan for testing
Exclusion Criteria
  • Regularly exercising(30 minute per day, 3 times per week)
  • Orthopedic or musculoskeletal condition that limits weight bearing
  • Uncontrolled atrial fibrillation
  • History of heart valve replacement
  • Unstable or serious medical condition (ie. on dialysis, oxygen; severe anemia, uncontrolled blood pressure or coronary artery disease)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
6 minute walkBaseline, 12 weeks, 24 weeks
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University of Michigan Mobility Research Center

🇺🇸

Ann Arbor, Michigan, United States

University of Michigan Mobility Research Center
🇺🇸Ann Arbor, Michigan, United States

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