Role of Exercise in Diastolic Heart Failure

Not Applicable

Completed

• Conditions: Heart Failure With Preserved Ejection Fraction; Diastolic Heart Failure
• Interventions: Behavioral: Health education and independent walking; Behavioral: Functional circuit training and lifestyle counseling

• Registration Number: NCT01047631
• Lead Sponsor: University of Michigan

Brief Summary

Diastolic heart failure is now being recognized as a key form of heart failure in older people. The focus of this research is to study ways to improve and maintain physical activity and functioning. This knowledge may improve the health and well-being in people with diastolic heart failure.

Detailed Description

The purpose of this project is to better understand how endurance and fatigue relate to performing daily activities and how we might better improve endurance and reduce fatigue through an exercise program.

Study Timeline

• Study Start: 2008-12
• Status Verified: 2010-01
• Study First Submitted: 2010-01-12
• Study First Submitted QC: 2010-01-12
• Study First Posted: 2010-01-13
• Primary Completion: 2011-12
• Study Completion: 2012-03
• Last Update Submitted: 2015-05-27
• Last Update Posted: 2015-05-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age 60 and over
• Evidence of diastolic dysfunction on echocardiogram
• Normal Left Ventricular Function (LVEF≥50%)
• Heart Failure-NYHA Class II/III
• Able and willing to participate in exercise program
• Able to come to Ann Arbor Michigan for testing

Exclusion Criteria

• Regularly exercising(30 minute per day, 3 times per week)
• Orthopedic or musculoskeletal condition that limits weight bearing
• Uncontrolled atrial fibrillation
• History of heart valve replacement
• Unstable or serious medical condition (ie. on dialysis, oxygen; severe anemia, uncontrolled blood pressure or coronary artery disease)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Health education and independent walking	Health education and independent walking	-
Functional circuit training and lifestyle counseling	Functional circuit training and lifestyle counseling	-

Primary Outcome Measures

Name	Time	Method
6 minute walk	Baseline, 12 weeks, 24 weeks

Trial Locations

Locations (1)

University of Michigan Mobility Research Center; 🇺🇸 Ann Arbor, Michigan, United States