DZHK Translational Registry for Cardiomyopathies

• Conditions: E85; I40; I42; Amyloidosis; Acute myocarditis; Cardiomyopathy

• Registration Number: DRKS00008017
• Lead Sponsor: niversitätsklinikum Heidelberg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-04-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 2307

Inclusion Criteria

Hereditary and inflammatory dilated cardiomyopathy (DCM)
-Left ventricular dilatation (left ventricular end-diastolic diameter >117%)
-Left ventricular systolic dysfunction
-Hypertrophic cardiomyopathy (HCM)
-Left ventricular non-compaction (LVNC)
-Arrhythmogenic right ventricular cardiomyopathy (ARVC)
-Amyloidosis
-Myocarditis

Exclusion Criteria

- <18 years, >80 years
-Other cardiac diseases:
-Severe arterial hypertension
-Primary pulmonary artery hypertension
-Chronic advanced non-cardiac diseases
-History of thorax radiation (life-long)
-Drug and alcohol abuse
-life expectancy <1 year due to non-cardiac diseases

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint in the TORCH-registry is all-cause death.

Secondary Outcome Measures

Name	Time	Method
The secondary outcomes are cardiovascular death, adequate ICD shock, survived sudden cardiac death, syncope or documented potentially life-threatening arrhythmia, cardiac transplantation, hospitalization due to the worsening of heart failure, and any non-elective cardiovascular hospitalization.