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Role of presence of protein in urine and decreased protein in blood as predictors of outcome in very ill patients admitted to the intensive care unit

Not Applicable
Conditions
Health Condition 1: R808- Other proteinuria
Registration Number
CTRI/2023/01/048671
Lead Sponsor
Vmmc and safdarajang hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Patients more than or equal to18 years of age

2. Admission in the ICU of more than 24 hours

Exclusion Criteria

1. Pregnancy / menstruating females

2. Urinary tract infection / Nephropathy

3. Anuria / macroscopic hematuria

4. Preexisting chronic kidney disease / significant proteinuria / renal replacement therapy

5. Disseminated malignancy

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To correlate microalbuminuria and hypoalbuminemia with mortality in critically ill patients <br/ ><br>admitted to the intensive care unit.Timepoint: 1. At time of admission to intensive care unit. <br/ ><br>2. After 6 hours of admission to intensive care unit. <br/ ><br>3. After 24 hours of admission to intensive care unit.
Secondary Outcome Measures
NameTimeMethod
To correlate microalbuminuria and hypoalbuminemia with: <br/ ><br>1. Days of mechanical ventilation <br/ ><br>2. APACHE II scores <br/ ><br>3. SOFA scores <br/ ><br>in critically ill patients admitted to the intensive care unit.Timepoint: DAY 1 OF ADMISSION: <br/ ><br>1. Serum creatinine, serum albumin (ALB 2), Blood urea nitrogen. <br/ ><br>2. Spot Urine samples after 24 hours of admission for albumin creatinine ratio (ACR 2). <br/ ><br>3. Any other investigations as required. <br/ ><br>4. Urine output for 24 hours on hourly and daily basis.
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