EUCTR2011-001510-33-GBActive, not recruitingPhase 1
The Efficacy of Continuous Intra-articular Infusion of Local Anaesthetic Agent following Elective Primary Hip Arthroplasty - LIA Hip Study
eeds Teaching Hospitals R and D department0 sites90 target enrollmentStarted: August 21, 2012Last updated:
Trial Snapshot
- Phase
- Phase 1
- Status
- Active, not recruiting
- Sponsor
- Enrollment
- 90
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional clinical trial of medicinal product
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •Men and women aged 18-99 • ASA 1-3 • Able to give informed consent • Fit to undergo elective primary total hip arthroplasty
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 42
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 28
Exclusion Criteria
- •Any patient already taking opioid analgesia or NSAIDs including aspirin • Allergy/sensitivity to local anaesthetics agents • Allergy/sensitivity to NSAIDs • Allergy/sensitivity to adrenaline • Patients taking anti-coagulant medication • Severe liver disease • Severely impaired renal function • Severe heart failure • Active cerebrovascular bleeding • Severe coagulation disorders • Severe asthma or previous bronchospasm with NSAIDs • Porphyria • Active peptic ulcer disease or acute GI bleed • Any patient unable to consent or understand the pump function • Bilateral hip replacements • Pregnancy/lactation (routine pregnancy tests are carried out pre-operatively on all patients of child bearing age) • Any patient already enrolled in another study
Investigators
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