Comparison of the Effects of Single Versus Triple Injections of Platelet-Rich Plasma in Patients With Knee Osteoarthritis
Not Applicable
Completed
- Conditions
- Knee Osteoarthritis
- Registration Number
- NCT06408922
- Lead Sponsor
- Izmir Democracy University
- Brief Summary
80 patients diagnosed with knee osteoarthritis were randomized into two groups: patients in Group 1 received a single intraarticular injection of PRP whereas those in group 2 were administered three intraarticular injections of PRP within an interval of 2 weeks between each application. Patients were evaluated before the treatment and at the 6 month after the treatment with a Visual Analog Scale (VAS) and The Western Ontario and MacMaster Universities (WOMAC) Osteoarthritis Index.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- ages of 35 and 80
- Kellgren-Lawrence grade of 2, 3, or 4
Exclusion Criteria
- rheumatic diseases, coagulopathies, severe cardiovascular diseases, local infections, malignancies, immunodeficiency, schizophrenia, mental retardation, anticoagulant therapy, a hemoglobin concentration of 11 g/dL and platelets of 150,000/L, a history of severe trauma, or a history of hyaluronic acid or corticosteroid injection within the previous 6 months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method The Western Ontario and MacMaster Universities (WOMAC) Osteoarthritis Index baseline and 6 months
- Secondary Outcome Measures
Name Time Method Visual Analog Scale (VAS) baseline and 6 months
Trial Locations
- Locations (1)
Buca Seyfi Demirsoy Training and Research Hospital
🇹🇷Izmir, Turkey
Buca Seyfi Demirsoy Training and Research Hospital🇹🇷Izmir, Turkey