Comparison between magnesium sulphate and lignocaine for preventing stress on heart during laryngoscopy and endotracheal intubation in patients undergoing surgeries under general anesthesia
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/10/058354
- Lead Sponsor
- Dr Prabhakar Kore Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. ASA physical status I and II
2. Patients undergoing elective surgeries under general anesthesia
3. Patients providing consent
Exclusion Criteria
1. Patients allergic to drugs under study
2. Patients with contraindication to general anesthesia
3. Patient refusal or who are unable to give consent
4. Patients undergoing emergency surgeries
5. Patients with significant cardiac and respiratory diseases
6. Patients with difficult airway
7. Pregnancy
8. Patients with oral and nasal pathology
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare intravenous lignocaine with intravenous magnesium sulphate with respect to: <br/ ><br>Hemodynamic variables - Mean arterial pressure, Systolic blood pressure, Diastolic blood pressure, Heart rateTimepoint: At baseline (before intubation), and at 1 min, 2 min, 3 min, 4min, 5min, 7 min, 10 min after intubation
- Secondary Outcome Measures
Name Time Method Incidence of side effects & complications if any of the study drugsTimepoint: From the time of administering the drugs till the end of the surgical procedure