Effects of the Physical Fitness on Serum Klotho Levels in Healthy Population

Not Applicable

Completed

• Conditions: Healthy Population
• Interventions: Other: Aerobic exercise; Other: plyometric exercise

• Registration Number: NCT03509818
• Lead Sponsor: Universidad Europea de Madrid

Brief Summary

Exercise program in serum Klotho levels

Detailed Description

This study aims to analiyze the effects of acute exercise in serum Klotho levels attending physical fitness in healthy population

Study Timeline

• Study First Submitted: 2018-03-19
• Study Start: 2018-03-21
• Study First Submitted QC: 2018-04-16
• Study First Posted: 2018-04-26
• Primary Completion: 2018-10-30
• Study Completion: 2019-03-26
• Status Verified: 2019-07
• Last Update Submitted: 2019-07-22
• Last Update Posted: 2019-07-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 85

Inclusion Criteria

• healthy people between 20 and 45 years old

Exclusion Criteria

• acute and chronic disease, people who take medication and supplements, smoker.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Aerobic	Aerobic exercise	Effects of aerobic acute exercise
Plyometric	plyometric exercise	Effects of plyometric acute exercise

Primary Outcome Measures

Name	Time	Method
Change in serum Klotho levels	Baseline and one hour	Change from baseline to acute exercise session

Secondary Outcome Measures

Name	Time	Method
Change in Cardiorespiratory Fitness VO2max	Baseline	For this Variable All people Will perform a exercise test on treadmill (Tecnhogym run race 1400HC; Gambettola, Italy), in this way we determinate the VO2max. Through the modifies Balke protocol. The gas Exchange data Will measured breath by breath using open circuit spirometry and specific face mask for Fitmate, Cosmed; Vmax 29C, Sensormedics machine.
Change in Body Composition	Baseline	The age in years; height in centimeters (tallimeter Ano Sayol SL, Barcelona, Spain); weight in kilograms (Inbody 720, Microcaya) and we can derive from this data the variable of Body Mass Index (BMI) calculated as weight (kg)/height (m2).
Change in Body Composition, Body muscle mass Index	Baseline	For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)
Change in Body Composition, % of Fat Mass	Baseline	For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)
Change in Body Composition, Total Muscle Mass	Baseline	For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)
Change in Body Composition, Visceral Fat Index.	Baseline	For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA). This value is really important to determine a cardiovascular risk.

Trial Locations

Locations (1)

Escuela de Doctorado e Invesitgacion, Universidad Europea; 🇪🇸 Madrid, Villaviciosa De Odon, Spain