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临床试验/NCT00599703
NCT00599703已完成不适用

Reorganization of Language Function in Patients With Brain Tumors

Memorial Sloan Kettering Cancer Center1 个研究点 分布在 1 个国家目标入组 7 人开始时间: 2005年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
7
试验地点
1
主要终点
To identify language organization prior to surgery in patients in whom a tumor invades or is directly adjacent to the expected location of one of the language centers.

研究概览

简要总结

The purpose of this study is to use an imaging method called functional magnetic resonance imaging (fMRI) in patients who have a tumor near an area of the brain that is believed to control language. The fMRI is a new kind of imaging that uses a strong magnetic field to look at functioning brain tissue. This kind of imaging will be used to study the effect of the brain tumor on your speech.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patient in whom a tumor invades or is directly adjacent to the expected location of one of the language centers.
  • At least 18 years of age
  • English as first language

排除标准

  • Patients with high grade tumors
  • History of significant psychiatric condition (e.g. schizophrenia, obsessive-compulsive disorder, significant dementia),
  • History of the following neurological conditions: CVA, demyelinating conditions, cerebral palsy, Alzheimer's disease.
  • History of significant claustrophobic reactions.
  • Pregnancy
  • Standard contraindications to MR examinations (e.g. implanted stimulator)
  • Patients, who were treated prior to our first scan, will not be eligible to participate in this study

结局指标

主要结局

To identify language organization prior to surgery in patients in whom a tumor invades or is directly adjacent to the expected location of one of the language centers.

时间窗: conclusion of study

次要结局

  • To assess language reorganization over time.(conclusion of study)

研究者

申办方类型
Other

研究点 (1)

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