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Clinical Trials/NCT00599703
NCT00599703
Completed
Not Applicable

Reorganization of Language Function in Patients With Brain Tumors

Memorial Sloan Kettering Cancer Center1 site in 1 country7 target enrollmentMay 2005

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Brain Cancer
Sponsor
Memorial Sloan Kettering Cancer Center
Enrollment
7
Locations
1
Primary Endpoint
To identify language organization prior to surgery in patients in whom a tumor invades or is directly adjacent to the expected location of one of the language centers.
Status
Completed
Last Updated
16 years ago

Overview

Brief Summary

The purpose of this study is to use an imaging method called functional magnetic resonance imaging (fMRI) in patients who have a tumor near an area of the brain that is believed to control language. The fMRI is a new kind of imaging that uses a strong magnetic field to look at functioning brain tissue. This kind of imaging will be used to study the effect of the brain tumor on your speech.

Registry
clinicaltrials.gov
Start Date
May 2005
End Date
March 2009
Last Updated
16 years ago
Study Type
Observational
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Patient in whom a tumor invades or is directly adjacent to the expected location of one of the language centers.
  • At least 18 years of age
  • English as first language

Exclusion Criteria

  • Patients with high grade tumors
  • History of significant psychiatric condition (e.g. schizophrenia, obsessive-compulsive disorder, significant dementia),
  • History of the following neurological conditions: CVA, demyelinating conditions, cerebral palsy, Alzheimer's disease.
  • History of significant claustrophobic reactions.
  • Pregnancy
  • Standard contraindications to MR examinations (e.g. implanted stimulator)
  • Patients, who were treated prior to our first scan, will not be eligible to participate in this study

Outcomes

Primary Outcomes

To identify language organization prior to surgery in patients in whom a tumor invades or is directly adjacent to the expected location of one of the language centers.

Time Frame: conclusion of study

Secondary Outcomes

  • To assess language reorganization over time.(conclusion of study)

Study Sites (1)

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