Identification of inflammatory mediators in spinal liquor and the knee in relation to synovial nerve sprouting and pain in osteoarthritis
Recruiting
- Conditions
- Osteoarthritis10023213
- Registration Number
- NL-OMON49579
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 125
Inclusion Criteria
In order to be eligible to participate in this study, a subject must meet the
following criteria:
• At least 18 years of age
• Be eligible for TKR under spinal anaesthesia, according to routine clinical
practice.
• Able and willing to give written informed consent
Exclusion Criteria
• Auto-immune disease or diabetes mellitus because they may also affect the
sensory system.
• Use of (pain) medication other than acetaminophen/paracetamol, NSAIDs and/or
opioids.
• Polyneuropathy or other neurologic disease that might affect outcome
measures.
• Major cognitive or psychiatric disorders.
• Problems with communication (language, deafness, aphasia etc.)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method