ew regimen of therapy in the treatment of Bronchiolitis

Phase 2

• Conditions: acute bronchiolitis; bronchiolitis.

• Registration Number: IRCT201108187371N1
• Lead Sponsor: Vice chancellory for Research, Zahedan University of Medical Sceiences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

ages 4 weeks to 12 months; clinical diagnosis of viral bronchiolitis as the primary reason for hospitalization; presence of an oxygen requirement and a minimum severity score of 1. Exclusion criteria: history of chronic neurologic, heart, kidney, or lung disease; history of prematurity <34 weeks gestation; severity score of >10; use of nebulized albuterol or nebulized epinephrine within 4 hours of study enrollment; use of nasal phenylephrine or oxymetazoline within 12 hours of study enrollment; or unstable” vital signs. Unstable” vital signs are defined as heart rate >200 beats/min, blood pressure 2 standard deviations above or below the age appropriate mean, and respiratory rate above 80 breaths/min. The choice of maximum score is somewhat arbitrary but would exclude patients with all of the following: respiratory rate =70 breaths/min; intercostal, substernal and supraclavicular retractions; no feeding; and inspiratory and expiratory wheezing or diminished breath sounds.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Respiratory distress. Timepoint: 30 minutes after completion of therapy. Method of measurement: physical examination.

Secondary Outcome Measures

Name	Time	Method
Pulse rate. Timepoint: 30 minutes after completion of therapy. Method of measurement: physical examination.;O2 saturation. Timepoint: 30 minutes after completion of therapy. Method of measurement: physical examination.;Dyspenea. Timepoint: 30 minutes after completion of therapy. Method of measurement: physical examination.;Retraction. Timepoint: 30 minutes after completion of therapy. Method of measurement: physical examination.