eft Ventricular Ejection Fraction before and after bariatic surgery
Completed
- Conditions
- (Morbide) ObesitasfatnessObesity1001928010017998
- Registration Number
- NL-OMON40367
- Lead Sponsor
- Maasstadziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
Age between 18 and 60 years
BMI > 40 kg/m2 or BMI > 35 kg/m2 with comorbidity (DM, lung problems, joint complaints)
Several registrated efforts of weightloss, guarded by a dietician
Exclusion Criteria
Age < 18 and > 60 years
Personality disorders / alcohol or drugs abuse
< 5 years of adiposity
No serious attemps of weightloss
Obesity caused by hormonal of metabolic disorders, no willingness for analysis of such disorders or lifelong check-ups
Change in medication to prevent atherosclerosis (statins)
Diameter > 65 cm (MRI diameter)
Standard contra indications for MRI
Congenital heart disease, known cardiomyopathy, ischaemic heart disease, heart infarction, myocarditis.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Increase in left ventricular function after bariatic surgery.<br /><br>The most important variables are not clear/uncertain due to a lack of relevant<br /><br>literature regarding the primary objective in combination with a MRI of the<br /><br>heart. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Differences in certain levels in blood samples<br /><br>Reduction of paracardial fat after bariatic surgery<br /><br>Reduction of visceral abdominal fat after bariatic surgery<br /><br>Reduction of hepatic steosis after bariatic surgery<br /><br>Increase in compliance of the thoracic aorta<br /><br>Anthropometric measurements before and after bariatic surgery<br /><br>Differences in measurements between the types of bariatic surgery</p><br>