Comparison of left ventricular ejection fraction obtained by using 3D echo modality called 3D EPSS with currently practiced methods of echo 2D EPSS, and 2D simpsons and 3D volumetric methods.
- Conditions
- Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery
- Registration Number
- CTRI/2023/07/055283
- Lead Sponsor
- Sree Chitra Tirunal Institute for Medical Sciences and Technology Trivandrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
All adults above 18 years of age, in sinus rhythm, admitted with CAD for elective CABG surgery will be included in the study.
1. Emergency surgeries
2. Redo surgeries
3. Patients not willing to participate in study
4. More than mild AR, MR or TR
5. Patients with Mitral valve pathology causing restricted or increased mobility of leaflets
6. Patients receiving preoperative inotropes
7. Patients with poor echo differentiation of endocardial borders
8. Patient with arrhythmias.
9. Contraindication to TEE probe placement like esophageal strictures, esophageal varices, esophageal
tumors, gastric ulcer, previous esophagectomy, esophageal diverticulum, tracheoesophageal fistula, previous bariatric surgery, hiatus hernia, large descending thoracic aortic aneurysm, unilateral vocal cord paralysis, esophageal varices, post-radiation therapy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Comparison of 2D mitral EPSS-based LVEF & 3D mitral EPSS-based LVEF with 2D LVEF measured <br/ ><br>from modified Simpsonâ??s formula in patients with normal LV systolic function (LVEF more than 52% in <br/ ><br>men & 54% in women) & their correlation with LVEF obtained by 3DE volumetric assessment as a reference method. <br/ ><br>2. Correlation of 3D mitral EPSS area with 2DE modified Simpsonâ??s LVEF & 3DE LVEF in patients with <br/ ><br>good LV & deranged LV function. We also would try to derive a formula to calculate LVEF using 3D <br/ ><br>EPSS area. <br/ ><br>Timepoint: Pre CPB initiation <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. Comparison of LVEF obtained by 2D & 3D mitral EPSS, modified Simpsonâ??s formula and their <br/ ><br>correlation with LVEF obtained by 3DE volumetric assessment as a reference method. <br/ ><br>i.) in patients with deranged LV systolic function <br/ ><br>ii.) in patients without dilated LV <br/ ><br>iii.) formula in patients with dilated LV <br/ ><br> <br/ ><br>2. Correlation of 3D mitral EPSS area with measured LVEF in patients with dilated LV and non-dilated <br/ ><br>LV. We also would try to derive a formula to calculate LVEF using 3D EPSS area. <br/ ><br>3. To assess the correlation between 3D EPSS on postoperative outcome parameters <br/ ><br>4. To ascertain the intraobserver variability and interobserver variability.Timepoint: Pre CPB initiation <br/ ><br>Post extubation <br/ ><br>Pre discharge from IC