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Clinical Trials/CTRI/2024/01/061175
CTRI/2024/01/061175
Not yet recruiting
Phase 3

Comparison of Optimal PEEP ventilation vs Prone position ventilation on changes in Regional Lung Ventilation in Patients with Acute Respiratory Distress Syndrome - A Randomized Clinical Trial - NI

JIPMER0 sites0 target enrollmentTBD
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Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Not specified
Sponsor
JIPMER
Status
Not yet recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
JIPMER

Eligibility Criteria

Inclusion Criteria

  • •1\.Age :18 \- 75 years
  • •2\.Diagnosis of ARDS according to Berlin’s criteria.
  • •a.Symptom begin within 1 week of insult, or new/worsening symptoms in last 1 week.
  • •b.Bilateral opacities on chest imaging
  • •c.PaO2/FiO2 \< 300 while on PEEP \> 5 cm H2O
  • •d.Not fully attributed to cardiac failure and / or volume overload
  • •3\.PaO2/FiO2 \<200
  • •4\.Anticipated duration of mechanical ventilation \>48 hours

Exclusion Criteria

  • •1\.Contraindication for prone positioning
  • •2\.Hemodynamic instability – Requirement of two or more vasopressor infusions to maintain target MAP.
  • •3\.Already receiving prone ventilation
  • •4\.Pregnancy

Outcomes

Primary Outcomes

Not specified

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