Comparison of blood pressure lowering effect of drugs.
Phase 4
- Conditions
- Health Condition 1: null- Hypertension
- Registration Number
- CTRI/2017/09/009725
- Lead Sponsor
- Indira Gandhi Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 134
Inclusion Criteria
1.Newly detected hypertensive patients with BP of >=160/100 mm Hg
2.Established hypertensive; off drug for one week with BP >160/100 to <180/110 mm Hg.
3.Patients age between 18 to 80 years.
4.Willingness to participate in the study.
Exclusion Criteria
1. Patients age <18 years and >80 years
2. Pregnancy & Lactating females
3. Renal or Hepatic disease
4. Congestive heart disease
5. Established CAD with and without MI
6. Known sensitivity to studied drugs
7. History of CVA & PVD
8. Patient unwilling to participate in the study
8. Elevation in BP >180/110 during withdrawal of antihypertensive drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the difference in Mean Systolic blood pressure and Diastolic blood pressure between Fixed dose combination group and Free drug combination groupTimepoint: 2 months
- Secondary Outcome Measures
Name Time Method 1.Change between groups in proportion of patient achieving target blood pressure <br/ ><br>2.Percentage reduction in Systolic and diastolic blood pressure from baseline blood pressureTimepoint: 2 months