Surgical Treatment of Aortic Valve Disease With Moderate Functional Mitral Regurgitation

Fuwai Yunnan Cardiovascular Hospital0 个研究点目标入组 154 人开始时间: 2022年10月最近更新: 2022年10月4日

适应症

试验速览

阶段: 不适用
状态: 尚未招募
发起方: Fuwai Yunnan Cardiovascular Hospital
入组人数: 154
主要终点: left ventricular global longitudinal strain

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

Debates exist on the treatment of moderate functional mitral regurgitation (FMR) in patients undergoing aortic valve replacement (AVR) for aortic valve disease. This study aims to evaluate the left ventricular function, which was evaluated through global longitudinal strain, after isolated AVR and AVR + mitral valve repair (MVr) in this group of patients.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Patients who received AVR (with or without concomitant MVr) from two center (Fuwai Yunnan Cardiovascular Hospital and Fuwai Hospital, Chinese Academy of Medical Sciences).
•Age more than 18 years.

排除标准

•Those with a history of rheumatic valvular disease or infective endocarditis.
•Primary mitral valve lesions.
•Patients receiving mitral valve replacement.
•Patient who refuse to participate in this study, or cannot complete 6-month follow-up after surgery.
•Age < 18 years.

结局指标

主要结局

left ventricular global longitudinal strain

时间窗: 10/10/2022-10/10/2023

The change of left ventricular global longitudinal strain compared to before surgery

次要结局

未报告次要终点

研究者

发起方

Fuwai Yunnan Cardiovascular Hospital

申办方类型

Other

责任方

Sponsor

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